Results 141 to 150 of about 453,295 (313)
Targeting of the prion protein to the cytosol: mechanisms and consequences
, 2010 Prion diseases are characterized by the conformational transition of the cellular prion protein (PrPC) into an aberrant protein conformer, designated scrapie-prion protein (PrPSc).
Miesbauer, M. +3 more
core
In vitro binding of L-triiodothyronine to receptors in rat liver nuclei. Kinectics of binding, extraction properties, and lack of requirement for cytosol proteins. [PDF]
, 1975 Martin I. Surks +2 more
openalex +1 more source
Vertical Nanostructures as Novel Interfaces for Brain Research
Advanced Materials Interfaces, EarlyView.This review highlights the unique features of vertical nanostructures (nanoneedles, nanostraws, nanopillars, and nanowires) for applications in brain research. Various characteristics of nanostructures, including material selection, fabrication methodology, and geometric designs, are discussed for their specific use in neurite guidance, neuron pinning,
Hao Nguyen Tran +3 more
wiley +1 more source
Ligandin retains and albumin loses bilirubin binding capacity in liver cytosol.
, 1978 Irving Listowsky +2 more
openalex +1 more source
Advanced Materials Interfaces, EarlyView.The interface between a conjugated polymer and phosphate buffer saline is modeled by employing multiphysics kinetic Monte Carlo simulation. Results demonstrate that the Marcus Gerischer theory is inadequate, and particle‐based simulation with molecular Marcus theory is required for accurate modeling.
Shengda Wang +5 more
wiley +1 more source
Elucidating Signal Transduction Modulatory Drug Target Network of Colon Cancer: A Network Biology Approach [PDF]
, 2010 Latest evaluation and validation of cancer drugs and their targets has demonstrated the lack and inadequate development of new and better drugs, based on available protocols.
Biplab Bhattacharjee +5 more
core +1 more source
Live Quantitative Characterization for Stem Cell Biomechanics
Advanced Materials Interfaces, EarlyView.These findings demonstrate an accessible technique for real‐time, high‐resolution mechanical mapping of live stem cells, without the use of specialised probes or advanced modelling techniques. This approach provides direct insight into localised cytoskeletal dynamics under chemical treatment and holds potential for broader application in understanding ...
Kaiwen Zhang +5 more
wiley +1 more source
The SNARE machinery is involved in apical plasma membrane trafficking in MDCK cells. [PDF]
, 1998 We have investigated the controversial involvement of components of the SNARE (soluble N-ethyl maleimide-sensitive factor [NSF] attachment protein [SNAP] receptor) machinery in membrane traffic to the apical plasma membrane of polarized epithelial (MDCK)
Chapin, SJ +6 more
core
Advanced Therapeutics, EarlyView.Cyclodextrin nanoparticle containing both Ga(NO3)3 and GaPP is synthesized and tested against non‐tuberculous mycobacteria (NTM). The in vivo efficacy of the nanoparticle therapy is additionally tested by treating pulmonary NTM infections in mice and observed much greater effectiveness in bacterial clearance and survival of mice.
Seoung‐ryoung Choi +2 more
wiley +1 more source
Liver cytosol corticosteroid binder IB, a new binding protein.
, 1975 Gerald Litwack, Sheila Rosenfield
openalex +1 more source