Results 161 to 170 of about 322,139 (355)

Transformation of the glucocorticoid receptor in rat liver cytosol by lysosomal enzymes.

, 1979
Jan Carlstedt‐Duke, Örjan Wränge, Erik Dahlberg, Jan-Ακε Gustafsson, B. Högberg   +4 more
openalex   +1 more source

Proteolysis at neutral pH in a lysosomal‐cytosol system can not be attributed to the uptake of proteins into lysosomes [PDF]

, 1974
W. Huisman, Lineke Lanting, J.M.W. Bouma, M. Gruber   +3 more
openalex   +1 more source

Emerging Nanotechnology Strategies for Obesity Therapy

Advanced Science, EarlyView.
Three types of nanomaterials used for obesity treatment are highlighted, including inorganic nanomaterials, organic nanomaterials and biomimetic nanomaterials. A detailed and comprehensive introduction to the recent nanotechnology strategies for obesity management is also provided, including drug delivery, photodynamic therapy, hyperthermia, gas ...
Weili Chang, Zhaoxu Meng, Yuezhu Zhao, Yake Qi, Zhou Li, He Lian   +5 more
wiley   +1 more source

Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy

Advanced Science, EarlyView.
This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao, Xianping Liu, Xu Chu, Feixiang Chen, Ruicheng Shi, Zonghao Liu, Yelin Wu, Yanyan Liu, Wenbo Bu   +8 more
wiley   +1 more source

Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export

Proceedings of the National Academy of Sciences of the United States of America, 2017
J. Grotzke, Patrycja Kozik, Jean-David Morel, Francis Impens, N. Pietrosemoli, P. Cresswell, S. Amigorena, C. Demangel   +7 more
semanticscholar   +1 more source

A Glycoproteome Data Mining Strategy for Characterizing Structural Features of Altered Glycans with Thymic Involution

Advanced Science, EarlyView.
This study presents a comprehensive data mining strategy for in‐depth extraction of overall and altered glycan features from structural and site‐specific glycoproteome data across various biomedical samples. The strategy enables the uncovery of four major altered glycan features associated with thymic involution and reveals their coordinated ...
Zhida Zhang, Yongqi Wu, Ke Hou, Yiwen Zhang, Lin Chen, Muyao Yang, Zhehui Jin, Yongchao Xu, Yingjie Zhang, Yinli Cai, Jiayu Zhao, Shisheng Sun   +11 more
wiley   +1 more source

Alterations in translatable messenger RNA coding for phosphoenolpyruvate carboxykinase (GTP) in rat liver cytosol during deinduction.

, 1978
D Kioussis, Lea Reshef, Hanah Cohen, S M Tilghman, Patrick B. Iynedjian, F J Ballard, Richard W. Hanson   +6 more
openalex   +1 more source

The estrogen cytosol receptor of female ovine pituitary [PDF]

, 1975
Phyllis M. Wise, Anita H. Payne
openalex   +1 more source

L-leucyl-L-leucine methyl ester does not release cysteine cathepsins to the cytosol but inactivates them in transiently permeabilized lysosomes

Journal of Cell Science, 2017
U. Repnik, Marita Borg Distefano, Martin Speth, Matthew Yoke Wui Ng, C. Progida, B. Hoflack, J. Gruenberg, G. Griffiths   +7 more
semanticscholar   +1 more source

A Nanomodulator Enhances Radiotherapy‐Induced In Situ Cancer Vaccine by Promoting Antigen‐Presenting of Tumor‐Associated Macrophage

Advanced Science, EarlyView.
A nanomodulator (Ft‐E64/Hf@Lipo) is developed, combining radiosensitizer hafnium (Hf) and the cysteine protease inhibitor E64, which cooperatively reinvigorated the antigen presentation of TAMs. Ft‐E64/Hf@Lipo sensitized‐RT generated abundant tumor neoantigens, and then E64/antigens, along with the apoptotic tumor cells, trafficked to TAMs via ...
Xiu Zhao, Mengli Li, Jun Li, Yueying Han, Yu Gong, Zhenzhong Zhang, Jinjin Shi, Cheng‐Yun Jin, Junjie Liu, Pilei Si   +9 more
wiley   +1 more source