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Cytosolic epoxide hydrolase

Chemico-Biological Interactions, 1988
Epoxide hydrolase activity is recovered in the high-speed supernatant fraction from the liver of all mammals so far examined, including man. For some as yet unexplained reason, the rat has a very low level of this activity, so that cytosolic epoxide hydrolase is generally studied in mice.
J, Meijer, J W, DePierre
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Cytosolic phospholipase A2

Journal of Lipid Mediators and Cell Signalling, 1995
To summarize the regulation of cPLA2, we have proposed a model for the activation of cPLA2 based both on our previous studies (Clark et al., 1991; Lin et al., 1993) and the work of many others (Fig. 5). In this model, cPLA2 is tightly regulated by multiple pathways, including those that control Ca2+ concentration, phosphorylation states and cPLA2 ...
J D, Clark   +3 more
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Cytosolic calcium oscillators

The FASEB Journal, 1988
Many cells display oscillations in intracellular calcium resulting from the periodic release of calcium from intracellular reservoirs. Frequencies are varied, but most oscillations have periods ranging from 5 to 60 s. For any given cell, frequency can vary depending on external conditions, particularly the concentration of natural ...
M J, Berridge, A, Galione
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Human cytosolic sulfotransferase SULT1A1

The International Journal of Biochemistry & Cell Biology, 2007
Sulfonation is an important conjugation reaction required for a range of biological processes including phase II metabolism, whereby sulfo-conjugation renders a compound more hydrophilic to aid its excretion. The major enzyme responsible for xenobiotic sulfonation is the widely expressed cytosolic sulfotransferase SULT1A1. The SULT1A1 crystal structure
Hempel, Nadine   +3 more
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A prostatic cytosol receptor

Biochemical and Biophysical Research Communications, 1970
Abstract Testosterone promotes the development of the prostate. It is partially transformed in the target organ into metabolites which have different effects upon the cells, and the activity of testosterone is possibly related to the formation of these derivatives (1, 2).
E E, Baulieu, I, Jung
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Mammalian Cytosolic Glutathione Transferases

Current Protein & Peptide Science, 2008
Glutathione Transferases (GSTs) are crucial enzymes in the cell detoxification process catalyzing the nucleophilic attack of glutathione (GSH) on toxic electrophilic substrates and producing a less dangerous compound. GSTs studies are of great importance since they have been implicated in the development of drug resistance in tumoral cells and are ...
Daniel F A R, Dourado   +2 more
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