Results 311 to 320 of about 322,139 (355)
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Pathways of chaperone-mediated protein folding in the cytosol
Nature Reviews Molecular Cell Biology, 2004Jason C Young
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Science, 2021
Microbiology Most human cells, not just those belonging to the immune system, mount protective responses to infection when activated by the immune cytokine interferon-gamma (IFN-γ). How IFN-γ confers this function in nonimmune cells and tissues is poorly understood. Gaudet et al. used genome-scale CRISPR/Cas9 gene editing to identify apolipoprotein L-3
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Microbiology Most human cells, not just those belonging to the immune system, mount protective responses to infection when activated by the immune cytokine interferon-gamma (IFN-γ). How IFN-γ confers this function in nonimmune cells and tissues is poorly understood. Gaudet et al. used genome-scale CRISPR/Cas9 gene editing to identify apolipoprotein L-3
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Chemico-Biological Interactions, 1988
Epoxide hydrolase activity is recovered in the high-speed supernatant fraction from the liver of all mammals so far examined, including man. For some as yet unexplained reason, the rat has a very low level of this activity, so that cytosolic epoxide hydrolase is generally studied in mice.
Joseph W. DePierre, Johan Meijer
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Epoxide hydrolase activity is recovered in the high-speed supernatant fraction from the liver of all mammals so far examined, including man. For some as yet unexplained reason, the rat has a very low level of this activity, so that cytosolic epoxide hydrolase is generally studied in mice.
Joseph W. DePierre, Johan Meijer
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Science, 2020
Coronavirus Coronaviruses transform host cell membranes into peculiar double-membrane vesicles that have long been thought to accommodate viral genome replication. However, because these compartments appeared to be completely sealed, it has remained unknown how the newly made viral RNA could be exported to the cytosol for translation and packaging into
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Coronavirus Coronaviruses transform host cell membranes into peculiar double-membrane vesicles that have long been thought to accommodate viral genome replication. However, because these compartments appeared to be completely sealed, it has remained unknown how the newly made viral RNA could be exported to the cytosol for translation and packaging into
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Transferrin in the reticulocyte cytosol
Biochimica et Biophysica Acta (BBA) - General Subjects, 1975Radioactive iodine-labeled iron-saturated human transferrin was shown to enter the cytosol of rabbit reticulocytes but not erythrocytes, and to be combined therein with a small "carrier" material not identical to the membrane transferrin receptor.
Dayle A. Sly +2 more
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The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol
Nature, 2001Yihong Ye, Hemmo H Meyer, Tom A Rapoport
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Trends in Biochemical Sciences, 2001
Various mammalian cells take up strains of virulent bacteria during the process of phagocytosis. When entering the host cells, bacteria can either live in a membrane-bound vacuole, modified to support their growth, or escape from the primary phagosome into the cytosol through the synthesis of specific proteins.
Peter Bayer, Tatiana A Surmacz
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Various mammalian cells take up strains of virulent bacteria during the process of phagocytosis. When entering the host cells, bacteria can either live in a membrane-bound vacuole, modified to support their growth, or escape from the primary phagosome into the cytosol through the synthesis of specific proteins.
Peter Bayer, Tatiana A Surmacz
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Journal of Lipid Mediators and Cell Signalling, 1995
To summarize the regulation of cPLA2, we have proposed a model for the activation of cPLA2 based both on our previous studies (Clark et al., 1991; Lin et al., 1993) and the work of many others (Fig. 5). In this model, cPLA2 is tightly regulated by multiple pathways, including those that control Ca2+ concentration, phosphorylation states and cPLA2 ...
Eric A. Nalefski +3 more
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To summarize the regulation of cPLA2, we have proposed a model for the activation of cPLA2 based both on our previous studies (Clark et al., 1991; Lin et al., 1993) and the work of many others (Fig. 5). In this model, cPLA2 is tightly regulated by multiple pathways, including those that control Ca2+ concentration, phosphorylation states and cPLA2 ...
Eric A. Nalefski +3 more
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Biochemical and Biophysical Research Communications, 1970
Abstract Testosterone promotes the development of the prostate. It is partially transformed in the target organ into metabolites which have different effects upon the cells, and the activity of testosterone is possibly related to the formation of these derivatives (1, 2).
Etienne-Emile Baulieu, Ingrid Jung
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Abstract Testosterone promotes the development of the prostate. It is partially transformed in the target organ into metabolites which have different effects upon the cells, and the activity of testosterone is possibly related to the formation of these derivatives (1, 2).
Etienne-Emile Baulieu, Ingrid Jung
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Caspase-11 Activation in Response to Bacterial Secretion Systems that Access the Host Cytosol
PLoS Pathogens, 2013 Inflammasome activation is important for antimicrobial defense because it induces cell death and regulates the secretion of IL-1 family cytokines, which play a critical role in inflammatory responses.
Cierra N Casson +2 more
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