Efficacy of CytoSorb®: a systematic review and meta-analysis [PDF]
Critical Care, 2023 Introduction Cytokine adsorption using the CytoSorb® adsorber has been proposed in various clinical settings including sepsis, ARDS, hyperinflammatory syndromes, cardiac surgery or recovery after cardiac arrest.
Sören Becker +5 more
doaj +3 more sources
Systemic Mastocytosis Successfully Managed using Cytosorb® During Cardiopulmonary Bypass for Aortic Valve Replacement [PDF]
Annals of Cardiac AnaesthesiaWe describe the case of a 72-year-old male with a history of systemic mastocytosis scheduled for on-pump aortic valve replacement for severe aortic insufficiency.
Adrien Gross +3 more
doaj +3 more sources
CytoSorb® Hemoadsorption as a Promising Tool to Handle COVID-19-Induced Cytokine Storm [PDF]
Case Reports in Critical Care, 2021 Accumulating evidence suggests that a patient subgroup with severe COVID-19 develops a cytokine release syndrome leading to capillary leakage and organ injury.
Alice-Christin Acevedo +5 more
doaj +3 more sources
Impact of CytoSorb® on interleukin-6 in cardiac surgery [PDF]
Frontiers in Cardiovascular Medicine, 2023 ObjectiveCardiac surgery is known to activate a cascade of inflammatory mediators leading to a systemic inflammatory response. Hemadsorption (HA) devices such as CytoSorb® have been postulated to mitigate an overshooting immune response, which is ...
Daniela Geisler +14 more
doaj +2 more sources
Antibiotics and Other Drugs Removal by the CytoSorb® Haemoadsorber: A Systematic Review of Available Evidence [PDF]
AntibioticsBackground/Objectives: Haemoadsorption has recently emerged as an extracorporeal treatment option for sepsis, septic shock, intoxications, and cardiac surgery to modulate dysregulated inflammatory responses or remove a wide range of circulating molecules.
Sara Kenda, Jakob Gubenšek, Tomaž Vovk
doaj +2 more sources
Early impact of CytoSorb® adsorber on proinflammatory cytokine plasmatic levels in a porcine model of refractory cardiogenic shock supported with VA-ECMO [PDF]
BMC Cardiovascular DisordersBackground Cardiogenic shock (CS) is a pejorative situation which often requires a circulatory support with VA-ECMO. However, VA-ECMO is known to trigger an inflammatory cascade with expression of proinflammatory cytokines Interleukin-6 (IL-6) and ...
Juliette Piccoli +9 more
doaj +2 more sources
Use of CytoSorb® hemoadsorption column during prolonged cardiopulmonary bypass in complex cardiac surgery patient [PDF]
Journal of Cardiothoracic Surgery, 2022 Background Complex cardiac surgery and prolonged cardiopulmonary bypass are associated with significant activation of the systemic inflammatory response system.
Marianne Alarie +3 more
doaj +2 more sources
The use of CytoSorb® in a prasugrel‐loaded patient undergoing emergent coronary artery bypass graft surgery [PDF]
Clinical Case Reports, 2023 Patients with acute coronary syndrome (ACS), failed percutaneous coronary intervention (PCI) and with an indication for emergent coronary artery bypass graft surgery (CABG) are at an increased risk of perioperative bleeding. Integration of the CytoSorb® (
Erich Moresco +3 more
doaj +2 more sources
Potential Clinical Use of CytoSorb® for Ticagrelor and Rivaroxaban Elimination Prior to Emergency Orthopedic Surgery in Trauma Patients [PDF]
LifeBackground: Major orthopedic trauma in patients receiving anticoagulants such as ticagrelor or rivaroxaban poses a significant perioperative challenge, particularly in emergency contexts where bleeding risks are heightened and specific reversal agents ...
Gabriele Melegari +10 more
doaj +2 more sources
Case Report: Prevention of Rhabdomyolysis-Associated Acute Kidney Injury by Extracorporeal Blood Purification With Cytosorb® [PDF]
Frontiers in Pediatrics, 2022 Acute kidney injury (AKI) is a severe complication of rhabdomyolysis. The pathophysiology of rhabdomyolysis-associated AKI is complex, but myoglobin related damage plays a major role.
Simon Rauch +7 more
doaj +2 more sources