In critically ill patients, liver dysfunction often results in coagulopathy and encephalopathy and is associated with high mortality. Extracorporeal clearance of hepatotoxic metabolites, including bilirubin and ammonia, aims to attenuate further ...
Desirée Tampe +2 more
exaly +5 more sources
Activated charcoal hemadsorption in Cerbera odollam poisoning
Cerbera odollam belongs to the poisonous Apocynaceae family, which grows in coastal salt swamps, creeks and along river banks found in South India. The poisonous part of the plant is the kernel containing the toxin cerberin which is a cardiac glycoside ...
Dyna Jones +3 more
doaj +3 more sources
CytoSorb® Hemadsorption in Cardiogenic Shock: A Real-World Analysis of Hemodynamics, Organ Function, and Clinical Outcomes During Mechanical Circulatory Support [PDF]
Background: Cardiogenic shock (CS), characterized by inadequate tissue perfusion due to cardiac dysfunction, has a high mortality rate despite advances in treatment. Systemic inflammation and organ failure exacerbate the severity of CS.
Julian Kreutz +10 more
doaj +3 more sources
Major endothelial damage markers identified from hemadsorption filters derived from treated patients with septic shock – endoplasmic reticulum stress and bikunin may play a role [PDF]
IntroductionIn septic patients the damage of the endothelial barrier is decisive leading to circulatory septic shock with disseminated vascular coagulation, edema and multiorgan failure.
Armando Rodríguez +2 more
exaly +4 more sources
CytoSorb® Hemadsorption During Microaxial Flow Pump (mAFP) Support in Cardiogenic Shock: A Propensity Score-Matched Cohort Study [PDF]
Background: Despite advances in temporary mechanical circulatory support (tMCS), patients with cardiogenic shock (CS) who are treated with a microaxial flow pump (mAFP; Impella®, Abiomed) still have a high mortality rate.
Julian Kreutz +7 more
doaj +2 more sources
Seraph® filter effectiveness in the treatment of circuit-related infections in ECMO patients—a single-center report [PDF]
IntroductionNosocomial infections in patients undergoing extracorporeal membrane oxygenation (ECMO) are common and associated with poorer outcomes. This study aimed to analyze the efficacy of the Seraph filter in reducing circuit-related infections and ...
Daniel Lovric +11 more
doaj +2 more sources
A Pool of Ferritin Nanoparticles Delivering Six Proteins of African Swine Fever Virus Induces Robust Humoral and Cellular Immune Responses in Pigs [PDF]
Background/Objectives: Inadequate characterization of protective antigens poses a significant challenge to the development of vaccines for African swine fever (ASF), particularly for antigen-dependent formulations such as subunit, mRNA, and recombinant ...
Zhanhao Lu +11 more
doaj +2 more sources
African warthog buffy coat cells retain susceptibility to African swine fever virus following whole blood transportation and storage [PDF]
The spread of African Swine Fever (ASF) across much of the world is a profound challenge to both domestic and wild Suidae populations. While vaccine and countermeasure development for domestic swine are ongoing, the understanding of ASF within wildlife ...
Jessica Mason +4 more
doaj +2 more sources
Efficacy of hemadsorption combining with cardiopulmonary bypass used in patients with acute type A aortic dissection [PDF]
Background It is hypothesized that combining HA380 with cardiopulmonary bypass (CPB) in acute type A aortic dissection (ATAAD) surgery could reduce the inflammatory response induced by CPB and subsequently improve prognosis.?
Shichao Guo +5 more
doaj +2 more sources
Challenges in the use of the CytoSorb® adsorber in an intensive care patient with liver dysfunction of unknown origin: a case report [PDF]
Background The treatment of critically ill patients in intensive care units is becoming increasingly complex. For example, organ transplants are regularly carried out, the recipients are seriously ill, and the postoperative course can be complicated ...
Caroline Gräfe +5 more
doaj +2 more sources

