Efficacy of CytoSorb®: a systematic review and meta-analysis [PDF]
Introduction Cytokine adsorption using the CytoSorb® adsorber has been proposed in various clinical settings including sepsis, ARDS, hyperinflammatory syndromes, cardiac surgery or recovery after cardiac arrest.
Sören Becker +5 more
doaj +3 more sources
Hematological parameter dynamics in critically ill patients treated with oXiris®-based CRRT and CytoSorb® hemoadsorption: a prospective single-center study [PDF]
Background Hemoadsorption is increasingly used as adjunctive extracorporeal support in sepsis and septic shock. Comparative data on device-specific hematologic effects remain limited. CytoSorb® and oXiris® are among the most widely applied hemoadsorption
Nikolina Špirić +9 more
doaj +3 more sources
Systemic Mastocytosis Successfully Managed using Cytosorb® During Cardiopulmonary Bypass for Aortic Valve Replacement [PDF]
We describe the case of a 72-year-old male with a history of systemic mastocytosis scheduled for on-pump aortic valve replacement for severe aortic insufficiency.
Adrien Gross +3 more
doaj +3 more sources
Potential Clinical Use of CytoSorb® for Ticagrelor and Rivaroxaban Elimination Prior to Emergency Orthopedic Surgery in Trauma Patients [PDF]
Background: Major orthopedic trauma in patients receiving anticoagulants such as ticagrelor or rivaroxaban poses a significant perioperative challenge, particularly in emergency contexts where bleeding risks are heightened and specific reversal agents ...
Gabriele Melegari +10 more
doaj +3 more sources
CytoSorb® Hemoadsorption as a Promising Tool to Handle COVID-19-Induced Cytokine Storm [PDF]
Accumulating evidence suggests that a patient subgroup with severe COVID-19 develops a cytokine release syndrome leading to capillary leakage and organ injury.
Alice-Christin Acevedo +5 more
doaj +3 more sources
Does the cytokine adsorber CytoSorb® reduce vancomycin exposure in critically ill patients with sepsis or septic shock? a prospective observational study [PDF]
Background Hemadsorption of cytokines is used in critically ill patients with sepsis or septic shock. Concerns have been raised that the cytokine adsorber CytoSorb® unintentionally adsorbs vancomycin.
Christina Scharf +9 more
doaj +2 more sources
Impact of CytoSorb® on interleukin-6 in cardiac surgery [PDF]
ObjectiveCardiac surgery is known to activate a cascade of inflammatory mediators leading to a systemic inflammatory response. Hemadsorption (HA) devices such as CytoSorb® have been postulated to mitigate an overshooting immune response, which is ...
Daniela Geisler +14 more
doaj +2 more sources
Antibiotics and Other Drugs Removal by the CytoSorb® Haemoadsorber: A Systematic Review of Available Evidence [PDF]
Background/Objectives: Haemoadsorption has recently emerged as an extracorporeal treatment option for sepsis, septic shock, intoxications, and cardiac surgery to modulate dysregulated inflammatory responses or remove a wide range of circulating molecules.
Sara Kenda, Jakob Gubenšek, Tomaž Vovk
doaj +2 more sources
Early impact of CytoSorb® adsorber on proinflammatory cytokine plasmatic levels in a porcine model of refractory cardiogenic shock supported with VA-ECMO [PDF]
Background Cardiogenic shock (CS) is a pejorative situation which often requires a circulatory support with VA-ECMO. However, VA-ECMO is known to trigger an inflammatory cascade with expression of proinflammatory cytokines Interleukin-6 (IL-6) and ...
Juliette Piccoli +9 more
doaj +2 more sources
CytoSorb® therapy: a new approach to treat critically ill patients with COVID-19 – a retrospective study [PDF]
Objective: The Coronavirus 2019 (COVID-19) pandemic has resulted in significant mortality and morbidity. Patients with severe COVID-19 infection experience cytokine storm that makes the treatment approach more challenging.
K. Patil, M. Priyadarsini
doaj +3 more sources

