Cytokine clearance with CytoSorb® during cardiac surgery: a pilot randomized controlled trial [PDF]
Critical Care, 2019 Background Cardiopulmonary bypass (CPB) is often associated with degrees of complex inflammatory response mediated by various cytokines. This response can, in severe cases, lead to systemic hypotension and organ dysfunction.
Elettra C Poli +8 more
doaj +3 more sources
CytoSorb® Hemadsorption in Cardiogenic Shock: A Real-World Analysis of Hemodynamics, Organ Function, and Clinical Outcomes During Mechanical Circulatory Support [PDF]
BiomedicinesBackground: Cardiogenic shock (CS), characterized by inadequate tissue perfusion due to cardiac dysfunction, has a high mortality rate despite advances in treatment. Systemic inflammation and organ failure exacerbate the severity of CS.
Julian Kreutz +10 more
doaj +3 more sources
Challenges in the use of the CytoSorb® adsorber in an intensive care patient with liver dysfunction of unknown origin: a case report [PDF]
Journal of Medical Case ReportsBackground The treatment of critically ill patients in intensive care units is becoming increasingly complex. For example, organ transplants are regularly carried out, the recipients are seriously ill, and the postoperative course can be complicated ...
Caroline Gräfe +5 more
doaj +3 more sources
Hemoadsorption Treatment with CytoSorb® in Probable Hemophagocytic Lymphohistiocytosis: A Role as Adjunctive Therapy? [PDF]
Case Reports in Hematology, 2021 Acute hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disease, with an annual incidence of 1 : 800,000 people. The disease is characterized by a cytokine storm, with concomitant macrophage and natural killer (NK) cell activation; death can
Samuele Ceruti +4 more
doaj +3 more sources
Dengue rhabdomyolysis successfully treated with hemoperfusion using CytoSorb® in combination with continuous renal replacement therapy: a case report [PDF]
Journal of Medical Case ReportsBackground Dengue fever is a mosquito-borne viral infection with a broad spectrum of clinical manifestations. Expanded dengue syndrome includes unusual manifestations that do not fall into the categories of dengue fever, dengue hemorrhagic fever, or ...
Piyum Samarasingha +4 more
doaj +3 more sources
A single centre experience with CytoSorb® as an adjunct therapy in critically ill patients with sepsis: a case series [PDF]
International Journal of Medical Device and Adjuvant Treatments, 2023 Objective: Sepsis is an immune response to infections that are caused by bacteria, viruses, fungi, or parasites. This potentially life-threatening condition is associated with high mortality and morbidity that causes a major global health burden and ...
H. Gajera, S. Gohil, A. Chhatravala
doaj +2 more sources
Does the cytokine adsorber CytoSorb® reduce vancomycin exposure in critically ill patients with sepsis or septic shock? a prospective observational study [PDF]
Annals of Intensive Care, 2022 Background Hemadsorption of cytokines is used in critically ill patients with sepsis or septic shock. Concerns have been raised that the cytokine adsorber CytoSorb® unintentionally adsorbs vancomycin.
Christina Scharf +9 more
doaj +2 more sources
CytoSorb® therapy: a new approach to treat critically ill patients with COVID-19 – a retrospective study [PDF]
International Journal of Medical Device and Adjuvant Treatments, 2023 Objective: The Coronavirus 2019 (COVID-19) pandemic has resulted in significant mortality and morbidity. Patients with severe COVID-19 infection experience cytokine storm that makes the treatment approach more challenging.
K. Patil, M. Priyadarsini
doaj +2 more sources
The use of CytoSorb hemoadsorption in critically ill patients: a narrative review [PDF]
Frontiers in MedicineInflammation, a complex biological response against injury or infection, is an important pathological basis for various critical diseases. A “normal” immune response exemplifies a balanced dialogue between immunological cells and a medley of pro- and ...
Kaixin Lei +7 more
doaj +2 more sources
CytoSorb® Hemadsorption During Microaxial Flow Pump (mAFP) Support in Cardiogenic Shock: A Propensity Score-Matched Cohort Study [PDF]
BiomedicinesBackground: Despite advances in temporary mechanical circulatory support (tMCS), patients with cardiogenic shock (CS) who are treated with a microaxial flow pump (mAFP; Impella®, Abiomed) still have a high mortality rate.
Julian Kreutz +7 more
doaj +2 more sources