Results 71 to 80 of about 528,622 (127)

International registry on the use of the CytoSorb® adsorber in ICU patients [PDF]

, 2019
INTRODUCTION: The aim of this clinical registry is to record the use of CytoSorb® adsorber device in critically ill patients under real-life conditions. METHODS: The registry records all relevant information in the course of product use, e. g., diagnosis,
Singer, M, Olboeter, D, Träger, K, Molnar, Z, Nierhaus, A, Bach, F, Schott, M, Weyland, A, Nitsch, M, Friesecke, S, Baumann, A, Tomescu, D, Grigoryev, E, Kielstein, JT, Meier-Hellmann, A, Bogdanski, R, Kellum, J, Kogelmann, K, Born, F, Nestler, F, Quintel, M, Schittek, GA, Haake, H, Jacob, D, Brunkhorst, FM, Schumacher, U   +25 more
core   +1 more source

Midkine Is Elevated After Multiple Trauma and Acts Directly on Human Cardiomyocytes by Altering Their Functionality and Metabolism

Frontiers in Immunology, 2019
Background and Purpose: Post-traumatic cardiac dysfunction often occurs in multiply injured patients (ISS ≥ 16). Next to direct cardiac injury, post-traumatic cardiac dysfunction is mostly induced by the release of inflammatory biomarkers.
Ina Lackner, Birte Weber, Meike Baur, Melanie Haffner-Luntzer, Tim Eiseler, Giorgio Fois, Florian Gebhard, Borna Relja, Ingo Marzi, Roman Pfeifer, Sascha Halvachizadeh, Miriam Lipiski, Nikola Cesarovic, Hans-Christoph Pape, Miriam Kalbitz, TREAT Research Group   +15 more
doaj   +1 more source

Extracorporeal Cytokine Hemadsorption for the Treatment of Severe Steroid Refractory Cytokine Release Syndrome Secondary to T‐Cell Immunotherapy for B‐Cell Malignancies: A Case Series

Hematological Oncology, Volume 44, Issue 4, July 2026.
Gianluca Cavallaro, Silvia Ferrari, Anna Pollastri, Elena Di Credico, Cristian Meli, Monica Rondi, Alessandro Putelli, Federico Lussana, Anna Grassi, Alessandro Rambaldi, Tino Martino Valetti, Ivano Riva, Giuseppe Gritti   +12 more
wiley   +1 more source

Kidney injury in patients with heart failure‐related cardiogenic shock: Results from an international, multicentre cohort study

European Journal of Heart Failure, Volume 27, Issue 11, Page 2397-2409, November 2025.
Kidney injury in heart failure‐related cardiogenic shock. AKI, acute kidney injury; CI, confidence interval; eCPR, extracorporeal cardiopulmonary resuscitation; eGFR, estimated glomerular filtration rate; HR, hazard ratio; OR, odds ratio; VA‐ECMO, veno‐arterial extracorporeal membrane oxygenation.
Jonas Sundermeyer, Caroline Kellner, Benedikt N. Beer, Lisa Besch, Angela Dettling, Letizia Fausta Bertoldi, Stefan Blankenberg, Jeroen Dauw, Dennis Eckner, Ingo Eitel, Tobias Graf, Patrick Horn, Joanna Jozwiak‐Nozdrzykowska, Paulus Kirchhof, Stefan Kluge, Axel Linke, Ulf Landmesser, Enzo Lüsebrink, Nicolas Majunke, Norman Mangner, Sven Möbius Winkler, Peter Nordbeck, Martin Orban, Federico Pappalardo, Matthias Pauschinger, Michal Pazdernik, Alastair Proudfoot, Matthew Kelham, Tienush Rassaf, Hermann Reichenspurner, Clemens Scherer, P. Christian Schulze, Robert H.G. Schwinger, Carsten Skurk, Marek Sramko, Guido Tavazzi, Holger Thiele, Luca Villanova, Nuccia Morici, Ephraim B. Winzer, Dirk Westermann, Benedikt Schrage   +41 more
wiley   +1 more source

Comparative evaluation of cytokine adsorption performance of a novel polymethylmethacrylate (PMMA)-based hemoadsorption cartridge and CytoSorb® in a porcine model of hypercytokinemia

Renal Replacement Therapy
Background Sepsis is defined as a condition in which the host’s response to infection becomes uncontrollable, leading to life-threatening organ damage. It is associated with the cytokine storm phenomenon, caused by excessive cytokine production.
Taku Miyasho, Chihiro Sugita, Takaharu Itami, Anju Yamaguchi, Mana Kamiya, Kazuto Yamashita   +5 more
doaj   +1 more source

Severe Vasoplegic Syndrome Treated with Angiotensin II and Hemoadsorption Therapy after Cardiac Surgery

Catheterization and Cardiovascular Interventions, Volume 106, Issue 3, Page 1740-1745, September 1, 2025.
ABSTRACT Vasoplegic syndrome (VS) is a common complication after cardiac surgery with cardiopulmonary bypass (CPB). The main pathophysiology mechanism of VS includes a systemic inflammatory response syndrome due to surgical trauma, release of pro‐inflammatory mediators caused by blood contact with foreign surfaces of heart‐lung machine (pump and tubing)
Matteo Lucchelli, Davide Tommaso Andreis, Mattia Gomarasca, Giovanni Mistraletti   +3 more
wiley   +1 more source

Use of Hemadsorption in a Case of Pediatric Toxic Shock Syndrome

Case Reports in Critical Care, 2017
Background. Toxic shock syndrome is a potentially fatal toxin-mediated disease. The role of toxins in this clinical entity made us hypothesize that extracorporeal blood purification with CytoSorb® could play a beneficial role in the clinical management ...
Andrea Berkes, Edit Szikszay, János Kappelmayer, Adrienne Kerényi, Tamás Szabó, László Ujhelyi, Krisztina Bari, György Balla, József Balla   +8 more
doaj   +1 more source

Broad adsorption of sepsis-related PAMP and DAMP molecules, mycotoxins, and cytokines from whole blood using CytoSorb® sorbent porous polymer beads. [PDF]

PLoS ONE, 2018
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. In sepsis and septic shock, pathogen-associated molecular pattern molecules (PAMPS), such as bacterial exotoxins, cause direct cellular damage ...
Maryann C Gruda, Karl-Gustav Ruggeberg, Pamela O'Sullivan, Tamaz Guliashvili, Andrew R Scheirer, Thomas D Golobish, Vincent J Capponi, Phillip P Chan   +7 more
doaj   +1 more source

Effects of empagliflozin on uric acid levels during acute heart failure recompensation: A sub‐analysis of the EMPAG‐HF trial (Effects of Empagliflozin on Diuresis and Renal Function in Patients with Acute Decompensated Heart Failure)

European Journal of Heart Failure, Volume 27, Issue 8, Page 1472-1478, August 2025.
Effects of empagliflozin on uric acid levels during acute heart failure recompensation. Abstract Background Sodium–glucose cotransporter 2 inhibitors improve prognosis in chronic heart failure as part of currently recommended therapeutic strategies.
Jurgen Bogoviku, Tien Dung Nguyen, Julian Georg Westphal, Franz Haertel, Pawel Aftanski, Sven Möbius‐Winkler, Martin Busch, P. Christian Schulze   +7 more
wiley   +1 more source

Current and novel biomarkers in cardiogenic shock

European Journal of Heart Failure, Volume 27, Issue 6, Page 1106-1125, June 2025.
A summary of current and novel biomarkers and their potential stages of release in cardiogenic shock. The diagram illustrates the proposed release of the biomarkers during the different stages of cardiogenic shock: progression from cardiac dysfunction/stress, through to inflammation and end‐organ dysfunction.
Victor Galusko, Florian A. Wenzl, Christophe Vandenbriele, Vasileios Panoulas, Thomas F. Lüscher, Diana A. Gorog   +5 more
wiley   +1 more source