Results 321 to 330 of about 11,083,244 (410)

Design and Evaluation of a <i>Zingiber officinale</i>-Kaolinite-Maltodextrin Delivery System: Antioxidant, Antimicrobial, and Cytotoxic Activity Assessment. [PDF]

Pharmaceutics
Segneanu AE, Bradu IA, Vlase G, Vlase T, Bejenaru C, Bejenaru LE, Mogoşanu GD, Ciocîlteu MV, Herea DD, Boia ER.   +9 more
europepmc   +1 more source

Generating Cell Surface Nucleated Hydrogels with an Artificial Membrane‐Binding Transglutaminase

Advanced Functional Materials, EarlyView.
Cell‐based therapies require advanced strategies to enhance cell delivery and bioactivity. Cell membrane engineering offers an avenue to impart new functions to delivered cells to boost their viability and function. Here, an artificial membrane‐binding transglutaminase is generated and biophysically characterized.
Rosalia Cuahtecontzi Delint, Tao Li, Kapil D. Patel, Will H. Zhang, Ben M. Carter, Graham J. Day, Adam W. Perriman   +6 more
wiley   +1 more source

Exploring the Biochemical Mechanism Beyond the Cytotoxic Activity of Sesquiterpene Lactones from Sicilian Accession of <i>Laserpitium siler</i> Subsp. <i>siculum</i> (Spreng.) Thell. [PDF]

Plants (Basel)
Vaglica A, Maggio A, Occhipinti C, Badalamenti N, Lauricella M, Bruno M, D'Anneo A.   +6 more
europepmc   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Asprecosides A-J, ten new pentacyclic triterpenoid glycosides with cytotoxic activity from the roots of Ilex asprella. [PDF]

Nat Prod Bioprospect
Wu Y, Zhang B, Li W, Peng L, Qiao W, Li W, Guo DA.   +6 more
europepmc   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

The Synthesis, Crystal Structure, Modification, and Cytotoxic Activity of α-Hydroxy-Alkylphosphonates. [PDF]

Molecules
Szalai Z, Kis AS, Takács A, Kőhidai L, Karaghiosoff K, Czugler M, Drahos L, Keglevich G.   +7 more
europepmc   +1 more source

Quantum‐Grade Nanodiamonds from a Single‐Step, Industrial‐Scale Pressure and Temperature Process

Advanced Functional Materials, EarlyView.
Novel method for creation of nitrogen‐vacancy centers in 50‐nm nanodiamonds based on high‐temperature plastic deformation is demonstrated. Compared to the electron irradiation approach, it yields nitrogen‐vacancy centers with significantly improved charge stability, T1 relaxation time, and optical Rabi contrast.
Yahua Bao, Michal Gulka, Parkarsh Kumar, Jakub Copak, Priyadharshini Balasubramanian, Yuliya Mindarava, Rémi Blinder, Michael Olney‐Fraser, Haotian Wen, Hana Spanielova, Helen Zhi Jie Zeng, Benjamin Whitefield, Igor Aharonovich, Jaroslav Hruby, Fedor Jelezko, J. Daniel Belnap, Shery L. Y. Chang, Petr Cigler   +17 more
wiley   +1 more source

In Vitro and In Silico Cytotoxic Activity of Isocordoin from <i>Adesmia balsamica</i> Against Cancer Cells. [PDF]

Int J Mol Sci
Silva V, Muñoz E, Ferreira C, Russo A, Villena J, Montenegro I, Birchmeier D, Madrid A.   +7 more
europepmc   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source