Results 321 to 330 of about 842,255 (343)

Cytotoxic activity of Origanum dictamnus

Fitoterapia, 2007
Several extracts of Origanum dictamnus, an endemic plant of Greece growing only in the island of Crete and the bioassay-directed isolated ursolic acid, were tested in vitro against the P388 (murine leukemia) and the human bronchial epidermoid cancer NSCLC-N6 (non small cell lung cancer) cell lines.
Dimitri Moreau, Christos Liolios, Ioanna Chinou, Christos Roussakis   +3 more
openaire   +3 more sources

Cytotoxic activities of fish leucocytes

Fish & Shellfish Immunology, 2006
Like mammalian leucocytes, white blood cells of fish are able to kill altered (e.g. virus-infected) and foreign (allogeneic or xenogeneic) cells. The existence of natural killer (NK)-like and specific cytotoxic cells in fish was first shown using allogeneic and xenogeneic effector/target cell systems.
Uwe Fischer, Bernd Köllner, Katrin Utke, Mitsuru Ototake, Tomonori Somamoto, Teruyuki Nakanishi   +5 more
openaire   +3 more sources

Activation of Cytotoxic Function in T Lymphocytes

The Journal of Immunology, 1976
Abstract The requirements for activation of cytotoxic function in mouse T lymphocytes were investigated. Initial generation of cytotoxicity in normal lymphocytes was equal in magnitude with either Con A or specific alloantigen, and in either case required DNA synthesis.
Heininger, D, Touton, M, Chakravarty, A K, Clark, W R   +3 more
openaire   +2 more sources

Activation of NK cell cytotoxicity

Molecular Immunology, 2005
Natural killer (NK) cells are innate effector lymphocytes necessary for defence against stressed, microbe-infected, or malignant cells. NK cells kill target cells by either of two major mechanisms that require direct contact between NK cells and target cells.
Kazuyoshi Takeda, Shayna E. A. Street, Mark J. Smyth, Hideo Yagita, Jennifer A. Westwood, Mariapia A. Degli-Esposti, Mariapia A. Degli-Esposti, Serani L.H. van Dommelen, Serani L.H. van Dommelen, Janice M. Kelly, Erika Cretney, Yoshihiro Hayakawa   +11 more
openaire   +4 more sources

Targeting and Activation of Cytotoxic Lymphocytes

2015
Des anticorps heteroconjugues ont permis d'etudier et de moduler la specificite des cellules cytotoxiques in vivo et in vitro. Il faut determiner quel anticorps bispecifique sera capable in vivo de «cibler» certaines cellules cytotoxiques qui pourront avoir des applications ...
David M. Segal, Denis P. Snider
openaire   +3 more sources

Cytotoxic activities of Stachys species

Fitoterapia, 2008
The cytotoxic activity of Stachys plants and of aucubin and harpagide against MCF7-breast adenocarcinoma, HeLa-cervix adenocarcinoma, A431-skin carcinoma of epithelial origin is reported in this study. Cisplatin and doxorubicin were use as reference compound.
István Zupkó, Borbála Réthy, Erzsébet Háznagy-Radnai, Gy. Falkay, Tamás A. Martinek, Imre Máthé, Imre Máthé, Sz. Czigle, Edit Wéber   +8 more
openaire   +4 more sources

Antiproliferative and Cytotoxic Activities

2018
Cancer is a genetic disease, affecting many people worldwide. Chemotherapy is routinely used for cancer treatment. However, this therapeutic approach is not always effective due to the development of cell resistance and toxic effects. Plants are a reservoir of natural chemicals with chemoprotective potential against cancer and with low adverse effects.
Claudia Anesini, Renzo Martino, Maria del Rosario Alonso   +2 more
openaire   +2 more sources

The cytolytic and cytotoxic activities of palytoxin

Toxicon, 2011
Palytoxin (PlTX) is one of the largest compound present in nature and, with its strong ability to modify the normal function of different biological systems, is also classified as one of the most potent biotoxins. Many alterations are triggered by PlTX, directly or indirectly related to its interaction with Na(+),K(+)-ATPase and the consequent ...
Simone Prandi, Mirella Bellocci, Gian Luca Sala   +2 more
openaire   +3 more sources

The antiherpesvirus activity and cytotoxicity of sangivamycin

Current Eye Research, 1987
Sangivamycin, 4-amino-5-carboxamido-7-(beta-D-ribofuranosyl)-pyrrolo[2,3-d]-pyrimidine is a structural analog of adenosine belonging to a group of nucleosides classified as pyrrolopyrimidines. Sangivamycin, an adenosine deaminase resistant analog, was found to inhibit the replication of three strains of herpes simplex virus type 1 (HSV-1) by 50% (ED50)
Paul S. Ritch, Jerry L. Taylor, Thomas P. O'malley, William J. O'Brien   +3 more
openaire   +3 more sources

Specific tumoricidal activity of cytotoxic macrophages and cytotoxic lymphocytes

Cancer Immunology, Immunotherapy, 1986
The antitumor potency and specificity of syngeneic immune peritoneal exudate cells were tested. Groups of DBA/2 mice were immunized against syngeneic SL2 tumor cells. Then 6 days after the last immunization the antitumor potency, and the specificity of the immunization reaction was tested by injecting groups of the immunized mice with 10(3) to 5 X 10(7)
Hub F.J. Dullens, A. Oostdijk, W. Den Otter, M. Van der Maas, W. Vuist, S. Schakenraad   +5 more
openaire   +2 more sources