Results 331 to 340 of about 842,255 (343)

Synthesis and evaluation of cytotoxic activity of arylfurans

European Journal of Medicinal Chemistry, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Renata Barbosa de Oliveira, Rodrigo S. Leite, Claudio Luis Donnici, Elaine Maria de Souza-Fagundes, Carlos L. Zani, Hellen A. J. Siqueira   +5 more
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Cytotoxic Activity of Tunicate Hemocytes

1996
Tunicates (protochordates) are filter-feeding marine invertebrates with a worldwide distribution. In their larval form, they exhibit many of the features characteristic of the vertebrates. The larva, with a tail, notochord, and dorsal neural tube, upon settlement undergoes a remarkable metamorphosis in which it loses most of its chordate ...
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Cytotoxic Activity and Apoptosis Induction by Gaillardin

Zeitschrift für Naturforschung C, 2013
Cytotoxic activity of gaillardin, a sesquiterpene lactone isolated from Inula oculus-christi L. (Asteraceae), was assessed in the human breast adenocarcinoma cell line MCF-7, human hepatocellular carcinoma cell line HepG-2, human non-small cell lung carcinoma cell line A-549, and human colon adenocarcinoma cell line HT-29, resulting in IC50 values of 6.
Mitra Asgharian Rezaie, Farzaneh Naghibi, Mahmoud Mosaddegh, Mahboobeh Irani, Azadeh Atoofi, Maryam Hamzeloo Moghadam   +5 more
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Synthesis of azolylalkylquinolines with cytotoxic activity

Journal of Heterocyclic Chemistry, 1996
AbstractThe syntheses of various azolylalkylquinoline derivatives in which the nature of the linkage between the quinoline and azolylalkyl moieties of the molecule were altered are described. The compounds were tested for cytotoxic activity towards cancer cells and compound 27 was found to exhibit moderate in vivo activity in a murine sarcoma model.
Dai Q. Nguyen, Ronald G. Micetich, Mark Abel, Hiep T. Luu, Mark Tempest, Mohsen Daneshtalab, A. Bernadette Oreski   +6 more
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Antimicrobial activity and cytotoxicity of Cirsium tenoreanum

Fitoterapia, 2004
The methanol and ethyl acetate extracts of the aerial parts of Cirsium tenoreanum, have been evaluated for their phytochemical constituents and antibacterial and cytotoxic properties. Three flavonoids, apigenin, quercetin-3-O-galactoside and kaempferol-3-O-ramnoside, were isolated. The ethyl acetate extract showed a good antiproliferative activity.
LOIZZO, Monica Rosa, STATTI, Giancarlo, TUNDIS, ROSA, Conforti F, ANDO', Sebastiano, Menichini F.   +5 more
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Regulation of Natural Cytotoxic Activity

1982
DISCUSSION INTRODUCER GUSTAVO CUDKOWICZ: If naturally occurring cytotoxic cells are to fulfill an important biological function, they will be integrated and they will be regulated. Only in the last few years have studies been conducted on NK cell regulation.
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Synthesis and cytotoxic activity of thiazolyl indolequinones

Anti-Cancer Drugs, 1999
A number of thiazolyl indolequinones have been prepared and evaluated for their antitumor properties. The compounds were synthesized from the appropriate indole, building up the thiazole ring using the Hantzsch reaction. Cytotoxic activity was determined in the human breast cancer SKBr3 cell line.
Moody, Christopher J., Roffey, Jonathan R A, Swann, Elizabeth, Lockyer, Stacey, Houlbrook, Susan, Stratford, Ian J.   +5 more
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Multiplex Caspase Activity and Cytotoxicity Assays

2008
Multiplexed assay chemistries provide for multiple measurements of cellular parameters within a single assay well. This experimental practice not only is more cost efficient but provides more informational content about a compound or treatment. For instance, multiplexed caspase activity assays can help establish the kinetics and magnitude of initiator ...
Andrew L. Niles, Richard A. Moravec, Terry L. Riss   +2 more
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Activation and Cytotoxic Activity of Macrophages: A Short Review

1976
Interaction of sensitized T-lymphocytes with specific antigen, as well as several other nonimmunological stimuli, will induce the appearance of new properties in macrophages collectively referred to as "activation". The importance of macrophage activation in various physiological processes is only just beginning to be understood.
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Macrophage activation for tumor cytotoxicity: regulatory mechanisms for induction and control of cytotoxic activity.

Federation proceedings, 1982
Macrophage activation for nonspecific tumor cytotoxicity occurs after completion of a series of reactions, each of which requires the simultaneous presence of effective activation signals and competent mononuclear phagocytes. This reaction sequence can be conceptually divided into three phases: precursor differentiation, priming, and trigger reactions,
Meltzer MS, Occhionero M, RUCO, Luigi
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