Results 161 to 170 of about 745,289 (215)

106P Optimisation of FAP-targeted small molecule drug conjugates for the delivery and release of cytotoxic payloads in solid tumors

ESMO Open
J.C. Mock, A. Galbiati, M. Bocci, A. Zana, E. Gilardoni, S. Cazzamalli, D. Neri   +6 more
openaire   +1 more source

Navigating Solid Tumor Heterogeneity: The Promise and Challenges of Antibody-Drug Conjugates. [PDF]

Cancer Heterog Plast
Duhon AA, McLean K.
europepmc   +1 more source

Immunological mechanisms and antibody-drug conjugates targeting B7-H3 and B7-H4 in ovarian cancer. [PDF]

Front Immunol
Brown EF, Colombo I, Madariaga A, Kasherman L.   +3 more
europepmc   +1 more source

Unlocking New Horizons: Antibody-Drug Conjugates in Small Cell Lung Cancer. [PDF]

Biology (Basel)
Liu J, Cui Y, Liao D, Sima M, Han M, Li W, Bi Y, Yue D.   +7 more
europepmc   +1 more source

Peptide-drug conjugates with linker-dependent payload release coordinate dual antitumor efficacy: Intrinsic RGDS-mediated metastasis suppression synergizes with camptothecin cytotoxicity

Biomedicine & Pharmacotherapy
Jianghao Cao, Zikang Zhang, Qiqi Feng, Yaonan Wang, Shurui Zhao, Xiaoyi Zhang, Ming Zhao   +6 more
openaire   +1 more source

Antibody-drug conjugates in breast oncology: new standards, emerging challenges, and future directions. [PDF]

Ther Adv Med Oncol
Bhardwaj PV, Tarantino P, Schlam I.
europepmc   +1 more source

SNAP-Tag-Based Antibody-Drug Conjugates Targeting Epidermal Growth Factor Receptor 1, Epidermal Growth Factor Receptor 2, Trophoblast Cell-Surface Antigen 2, and Tissue Factor for Ovarian Cancer Treatment. [PDF]

ACS Omega
Zhang C, Sheng W, Mohiuddin TM, Al-Rawe M, Schmitz R, Niebert M, Zeppernick F, Meinhold-Heerlein I, Hussain AF.   +8 more
europepmc   +1 more source

951 A novel splicing-targeted ADC payload drives immune activation, synergy with checkpoint inhibitors, and enhanced therapeutic potential beyond cytotoxicity

Regular and Young Investigator Award Abstracts
openaire   +1 more source