Results 171 to 180 of about 2,716,407 (409)

Evidence for Multiple Clones of Cytotoxic T Cells Responding to Antigenic Determinants on the Same Molecule [PDF]

, 1978
R Geib, Chinlee Chiang, Jan Klein
openalex   +1 more source

CD4 Helper and CD8 Cytotoxic T Cell Differentiation.

Annual Review of Immunology, 2018
I. Taniuchi
semanticscholar   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment

Cell Reports
Summary: Immune checkpoint inhibitors exert clinical efficacy against various types of cancer through reinvigoration of exhausted CD8+ T cells that attack cancer cells directly in the tumor microenvironment (TME).
Wenhao Zhou, Shusuke Kawashima, Takamasa Ishino, Katsushige Kawase, Youki Ueda, Kazuo Yamashita, Tomofumi Watanabe, Masahito Kawazu, Hiromichi Dansako, Yutaka Suzuki, Hiroyoshi Nishikawa, Takashi Inozume, Joji Nagasaki, Yosuke Togashi   +13 more
doaj   +1 more source

Pathogenetic role of tissue factor in graft-versus-host disease [PDF]

, 2008
Graft-versus-host disease (GVHD) is a serious complication after allogeneic stem cell transplantation, the mechanism of it is still not elucidated.
Li Quan, Li Weiming, Zhang Jian, Zou Ping   +3 more
core   +1 more source

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

FEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi, Saki Sugihara, Yohei Ishibashi, Kono Yushi, Hazuki Yamauchi, Motohiro Tani   +5 more
wiley   +1 more source

In vitro generation of antigen-specific helper T cells that collaborate with cytotoxic T-cell precursors.

, 1978
Linda L. Baum, L M Pilarski
openalex   +1 more source

Young F1 Mice Spontaneously Generate Cytotoxic T Cells against Parental Targets [PDF]

, 1979
Hiromichi Ishikawa, Richard Dutton
openalex   +1 more source

Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition

Nature, 1991
R. Phillips, S. Rowland-Jones, D. Nixon, F. Gotch, J. Edwards, A. Ogunlesi, J. Elvin, J. A. Rothbard, C. Bangham, C. Rizza, A. McMichael   +10 more
semanticscholar   +1 more source

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

FEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura, Kota Shoji, Michidai Nobe, Moe Ishikawa, Miu Tanaka, Akiko Okayama, Souichi Adachi, Hidemasa Matsuo   +7 more
wiley   +1 more source