Results 211 to 220 of about 216,752 (252)
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Inhibition of cytotoxic T lymphocytes with concanavalin A
Cellular Immunology, 1980Abstract Increasing concentrations of concanavalin A (ConA) were found to increasingly inhibit immunologically specific cytotoxic T lymphocyte (CTL)-mediated cytolysis. Even concentrations of ConA that best enabled nonspecific cytolysis were found to inhibit immunologically specific cytolysis by the same population of effector cells.
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Collaboration of helper and cytotoxic T lymphocytes
European Journal of Immunology, 1993AbstractCytotoxic T lymphocytes are major effector cells in responses to viral infections and in allograft rejection and are implicated in many other immunological reactions. Efficient induction of cytotoxic activity in these cells in many but not all cases depends upon helper Tand antigenāpresenting cells so that at least three different cell types ...
G, Stuhler, P, Walden
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Cytotoxic T Lymphocytes in Resistance to Tuberculosis
1998Recent experimental evidence has suggested T cells recognizing antigens in the context of both classical MHC class I and nonclassical class I-like molecules contribute to protective responses against Mycobacterium tuberculosis (MTB) infection. Our aims were to characterize both types of T cells, and to explore the basis of communication between the ...
R J, Mazzaccaro +6 more
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CD4 cytotoxic T lymphocyte differentiation
Biochimie, 1988In vitro allostimulated CD4+ human lymphocytes were cloned by micromanipulation and expanded for a short time in IL-2 conditioned medium. In the present study we observed that proliferative noncytotoxic cloned cells were able to acquire the specific cytolytic activity under some modification of the cloned cells restimulation cycle. We demonstrated that
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Radiosensitivity of Murine T-Lymphocyte Cytotoxicity
Radiation Research, 1984A biphasic curve was observed when surviving allogeneic lytic activity was plotted as a function of irradiation delivered before sensitization. Flow cytometry analysis demonstrated that the number of cells was reduced in response to increasing dose and that subset precursors Lyt 1+2+ were proportionally more radiosensitive than the other subsets ...
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