Results 151 to 160 of about 709,234 (313)

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

Evaluation of the in vitro biocompatibility of orthodontic elastics

tex has been extensively used in orthodontics since the advent of the specialty. Natural latex does not fall into the category of materials known to be entirely inoffensive. The objective of the present in vitro study is to test the hypothesis that there
Matheus Melo Pithon, Rogério Lacerda dos Santos, Fernanda Otaviano Martins, Maria Teresa Villela Romanos, Mônica Tirre de Souza Araújo
core  

Adenosine and 1,N⁶-Ethenoadenosine-Derived Nucleolipids: Synthesis, Lipophilicity (log<i>P</i>), and Cytotoxic Activity Compared to Conventional Cytostatics in Glioma and Glioblastoma Cell Lines. [PDF]

Int J Mol Sci
Lünswilken M, Bender-Arnst E, Barakat F, Leinweber E, Beginn U, Bonaterra GA, Kinscherf R.   +6 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Subtle cytotoxicity and genotoxicity differences in superparamagnetic iron oxide nanoparticles coated with various functional groups

, 2011
Seong Cheol Hong1,*, Jong Ho Lee1,*, Jaewook Lee1, Hyeon Yong Kim1, Jung Youn Park2, Johann Cho3, Jaebeom Lee1, Dong-Wook Han11Department of Nanomedical Engineering, BK21 Nano Fusion Technology Division, College of Nanoscience and Nanotechnology, Pusan ...
Park JY, Cho J, Kim HY, Hong SC, Lee J, Han DW, Lee JH   +6 more
core  

Ionic Liquids in Pharmaceuticals: A Scoping Review of Formulation Strategies

ACS Omega
Igor Luiz Gonçalves Pereira, Ana Luiza Ziulkoski, Karine Modolon Zepon, Luiz Alberto Kanis, Henri Stephan Schrekker   +4 more
doaj   +1 more source

Stress-activated pathways mediate PFAS effects on human placental syncytiotrophoblast cells. [PDF]

Toxicol Sci
Kozai K, Varberg KM.
europepmc   +1 more source

Incorporation of Selenium into Sol–Gel‐Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity

Advanced Engineering Materials, EarlyView.
Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni, Thalita Marcolan Valverde, Talita Martins, Guilherme Mattos Jardim Costa, Alfredo Miranda de Goes, Marcello Rosa Dumont, Eduardo Henrique Martins Nunes, Marivalda de Magalhães Pereira   +7 more
wiley   +1 more source

Magnetic fluid hyperthermia enhances cytotoxicity of bortezomib in sensitive and resistant cancer cell lines

, 2013
Merlis P Alvarez-Berríos,1 Amalchi Castillo,1 Carlos Rinaldi,1–3 Madeline Torres-Lugo1 1Department of Chemical Engineering, University of Puerto Rico, Mayagüez, Puerto Rico; 2J Crayton Pruitt Family Department of Biomedical Engineering,
Rinaldi C, Alvarez-Berríos MP, Torres-Lugo M, Castillo A   +3 more
core  

Rapid assessment of immune effector cell-mediated cytotoxicity using mRNA lipid nanoparticles. [PDF]

Front Immunol
Mollica P, Li J, Kim SH, Goncalves B, Chen Y, Bharti A, O'Neill D, Weber E, Alameh M, Ma L.   +9 more
europepmc   +1 more source