FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu +5 more
wiley +1 more source
Correction: Bioproduction, characterization, anticancer and antioxidant activities of extracellular melanin pigment produced by newly isolated microbial cell factories Streptomyces glaucescens NEAE-H. [PDF]
El-Naggar NE, El-Ewasy SM.
europepmc +1 more source
Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt +2 more
wiley +1 more source
Cytotoxicity of Piezoelectric Materials in Colony Formation Assay
Yasutomo UETSUJI +3 more
openalex +2 more sources
Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Biosupercapacitors for Human‐Powered Electronics
Biosupercapacitors are emerging as biocompatible and integrative energy systems for next‐generation bioelectronics, offering rapid charge–discharge performance and mechanical adaptability. This review systematically categorizes their applications from external to organ‐level systems and highlights their multifunctional roles in sensing, actuation, and ...
Suhyeon Kim +7 more
wiley +1 more source
Natural killer cell exhaustion in ovarian cancer: from molecular suppression to therapeutic revival. [PDF]
Ning J, Yao L.
europepmc +1 more source
Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions
An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park +10 more
wiley +1 more source
Lysyl Oxidase Promotes Actin-Dependent Neutrophil Activation and Cytotoxicity Toward Retinal Endothelial Cells in Diabetes. [PDF]
Agarwal M +6 more
europepmc +1 more source

