Results 161 to 170 of about 22,112 (211)

Released Granulocytic Elastase [PDF]

open access: yes, 1985
Duswald, Karl-Heimo   +3 more
core  

Gamma‐Glutamyl Cysteine Ligase Activity as a Proxy for Human T Cell Function and Drug‐Induced Immunosuppression

open access: yesAdvanced Science, EarlyView.
GLed, a reversible lanthanide‐based GSH sensor that enables real‐time, single‐cell measurement of Gamma–Glutamyl Cysteine Ligase (GCL) activity ‐whose role in human T cells remains unclear‐ is developed. GLed directly links GCL activity to T cell effector functions and reveals its modulation by immunosuppressive drugs, identifying GCL as a critical ...
Francisco Fueyo‐González   +9 more
wiley   +1 more source

Therapeutical Potential and Immunomodulatory Profile of <i>Arthrospira platensis</i> Compounds against Chagas Disease. [PDF]

open access: yesACS Infect Dis
da Silva MROB   +11 more
europepmc   +1 more source

IgG lymphocytotoxic antibodies in clinical liver transplantation: Studies toward further defining their significance [PDF]

open access: yes, 1995
Bronsther, S   +10 more
core  

Microsphere Strategy to Generate Conformal Bone Organoid Units with Osteoimmunomodulation and Sustainable Oxygen Supply for Bone Regeneration

open access: yesAdvanced Science, EarlyView.
Oxygen‐releasing immunomodulatory microspheres are used to construct conformal bone organoid units that enhance osteogenesis, angiogenesis, and immune regulation. By integrating BMSCs, macrophages, and CaO₂‐HAp into a SilMA‐based hydrogel platform, this strategy provides sustained oxygen supply and anti‐inflammatory microenvironments, leading to ...
Anfu Deng   +12 more
wiley   +1 more source

DHODH modulates immune evasion of cancer cells via CDP-Choline dependent regulation of phospholipid metabolism and ferroptosis. [PDF]

open access: yesNat Commun
Teng D   +11 more
europepmc   +1 more source

Pinosylvin Inhibits Inflammatory and Osteoclastogenesis via NLRP3 Inflammasome

open access: yesAdvanced Science, EarlyView.
Pinosylvin blocks LPS and RANKL induced NEK7/NLRP3 interaction, inhibiting NLRP3 inflammasome oligomerization and assembly, reducing IL‐1β maturation and GSDMD cleavage, and improving the inflammatory microenvironment and abnormal osteoclastogenesis. Abstract Pro‐inflammatory cytokines such as TNF, IL‐1, and IL‐6 trigger aberrant osteoclastogenesis and
Wei Zhang   +13 more
wiley   +1 more source

The Influence of Indisulam on Human Immune Effector Cells: Is a Combination with Immunotherapy Feasible? [PDF]

open access: yesPharmaceutics
Arnet L   +6 more
europepmc   +1 more source

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

open access: yesAdvanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai   +5 more
wiley   +1 more source

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