Resiquimod-loaded MOF525 enables synergistic photodynamic therapy and immunotherapy for colorectal cancer. [PDF]
Lee NK +12 more
europepmc +1 more source
The in vivo effect of hepatotrophic factors ALR, HGF, and IGF-II on natural killer cell functions [PDF]
Azzarone, A +8 more
core
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian +7 more
wiley +1 more source
Dietary Management of Eosinophilic Esophagitis in the Era of Molecular Diagnostics: The Role and Limitations of Component-Resolved Diagnostics-A Narrative Review. [PDF]
Wawrzeńczyk A +5 more
europepmc +1 more source
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Pregnancy Outcome following Administration of Intravenous Immunoglobulin in Women with Unexplained Recurrent Implantation Failure: A Retrospective Cohort Study. [PDF]
Aflatoonian A +5 more
europepmc +1 more source
Highly Biomimetic Ectodermal Epithelial Organoids for Epithelial Barrier Stimulation Assays
ABSTRACT Evaluating the potential toxicity of pharmaceuticals and biomaterials to ectodermal epithelia, such as the oral mucosa and skin, is indispensable in pre‐clinical assessments. However, this remains a challenge primarily owing to the lack of physiologically relevant and accurate screening models.
Yiming Chen +13 more
wiley +1 more source
Carbon dot-lipidoid nanocarriers for superiorly biocompatible nasal mRNA cancer vaccination. [PDF]
Kim H +7 more
europepmc +1 more source
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo +8 more
wiley +1 more source
CD8<sup>+</sup> T cell stemness precedes post-intervention control of HIV viraemia. [PDF]
Kiani Z +15 more
europepmc +1 more source

