Results 11 to 20 of about 364,305 (138)

In vitro evaluation of the cytotoxicity and eye irritation potential of preservatives widely used in cosmetics

Brazilian Journal of Pharmaceutical Sciences, 2022
has been increasing every year and is expected to reach $675 billion by 2020 at an estimated growth rate of 6.4% per year. Exposure to skin irritants is the major cause of non-immunological inflammation of the skin.
Gabriela de Oliveira Prado Corrêa, Danieli Camilo Marcato, Wagner Soares Ramos, M. Correa, R. Cicarelli, V. Isaac   +5 more
semanticscholar   +1 more source

Effect of allogeneic blood transfusion on neutrophil functional activity and lymphocyte cytotoxicity in recipient rabbits

Ukrainian journal of veterinary sciences, 2022
The relevance of this paper is that transfusion of allogeneic blood to recipient animals is always associated with immunological risks. In this regard, the purpose of this study was to assess the state of phagocytic activity of blood neutrophils by ...
Mykola Maliuk, J. Illek, M. Kulida, M. Savchuk, O. Yehorov   +4 more
semanticscholar   +1 more source

Persistent epstein-barr virus infection mimicking juvenile chronic myelogenous leukemia: immunologic and hematologic studies.

Blood, 1983
Epstein-Barr virus (EBV) infections may induce a diverse clinical picture, ranging from the well characterized infectious mononucleosis (IM) syndrome to the rare X-linked lymphoproliferative syndrome. We describe two unrelated children, a 21-mo-old white
H. Herrod, L. Dow, J. Sullivan
semanticscholar   +1 more source

Frequency and clinical implications of development of donor-specific and non-donor-specific HLA antibodies after kidney transplantation.

Journal of the American Society of Nephrology, 2005
The involvement of immunologic and nonimmunologic events in long-term kidney allograft failure is difficult to assess. The development of HLA antibodies after transplantation is the witness of ongoing reactivity against the transplant, and several ...
M. Hourmant, A. Cesbron-Gautier, P. Terasaki, K. Mizutani, A. Moreau, Aurélie Meurette, J. Dantal, M. Giral, G. Blancho, D. Cantarovich, G. Karam, G. Folléa, J. Soulillou, J. Bignon   +13 more
semanticscholar   +1 more source

Phenotype and function of natural killer cells in systemic lupus erythematosus: excess interferon-γ production in patients with active disease.

Arthritis & Rheumatism, 2011
OBJECTIVE To determine the phenotype and the functionality of natural killer (NK) cells in patients with systemic lupus erythematosus (SLE). METHODS A total of 94 patients with SLE (91 women and 3 men) were compared with 26 healthy controls. Active SLE
B. Hervier, V. Béziat, J. Haroche, A. Mathian, P. Lebon, P. Ghillani‐Dalbin, L. Musset, P. Debré, Z. Amoura, V. Vieillard   +9 more
semanticscholar   +1 more source

Stochastic model of T Cell repolarization during target elimination (I) [PDF]

, 2020
Cytotoxic T lymphocytes (T) and natural killer (NK) cells are the main cytotoxic killer cells of the human body to eliminate pathogen-infected or tumorigenic cells (i.e. target cells). Once a NK or T cell has identified a target cell, they form a tight contact zone, the immunological synapse (IS).
arxiv   +1 more source

AMG 701 induces cytotoxicity of multiple myeloma cells and depletes plasma cells in cynomolgus monkeys.

Blood Advances, 2020
Multiple myeloma (MM) is a hematologic malignancy that is characterized by the accumulation of abnormal plasma cells (PCs) in the bone marrow (BM). Patient outcome may be improved with BiTE (bispecific T-cell engager) molecules, which redirect T cells to
R. Goldstein, A. Goyos, Chi-Ming Li, Petra Deegen, P. Bogner, Alexander Sternjak, O. Thomas, M. Klinger, J. Wahl, M. Friedrich, B. Rattel, Edwin Lamas, Xiao Min, A. Sudom, Mozhgan Farshbaf, A. Coxon, M. Balazs, T. Arvedson   +17 more
semanticscholar   +1 more source

Citotoxicidad del glifosato en células mononucleares de sangre periférica humana

Biomédica: revista del Instituto Nacional de Salud, 2007
Introducción. El glifosato es un herbicida de amplio espectro, no selectivo, utilizado comúnmente en agricultura para eliminar malezas. Los estudios que han evaluado la toxicidad del glifosato en animales y en ambiente muestran que las formulaciones ...
Adriano Martínez, Ismael Reyes, Niradiz Reyes   +2 more
doaj   +1 more source

Stochastic model of T Cell repolarization during target elimination (II) [PDF]

, 2021
Cytotoxic T lymphocytes (T cells) and natural killer cells form a tight contact, the immunological synapse (IS), with target cells, where they release their lytic granules containing perforin/granzyme and cytokine containing vesicles. During this process the cell repolarizes and moves the microtubule organizing center (MTOC) towards the IS.
arxiv   +1 more source

Percutaneous BCG enhances innate effector antitumor cytotoxicity during treatment of bladder cancer: a translational clinical trial

Oncoimmunology, 2019
Background: Intravesical bacillus Calmette-Guérin (BCG) is the gold standard immunologic agent for treating patients with high-grade non-muscle invasive bladder cancer (NMIBC).
Niannian Ji, Neelam Mukherjee, Edwin E. Morales, Maggie E. Tomasini, V. Hurez, T. Curiel, G. Abate, D. Hoft, X. Zhao, J. Gelfond, S. Maiti, L. Cooper, R. Svatek   +12 more
semanticscholar   +1 more source