Results 71 to 80 of about 370,225 (281)

Recognition of viral glycoproteins by influenza A-specific cross- reactive cytolytic T lymphocytes [PDF]

open access: yes, 1980
Two populations of cytolytic T lymphocytes (CTL) generated after influenza A virus infection can be distinguished into one with specificity for the sensitizing hemagglutinin type and a second with cross-reactivity for antigens induced by other type-A ...
Allen, H.   +4 more
core   +2 more sources

Robust Systemic and Mucosal Immune Responses to Coxsackievirus B3 Elicited by Spider Silk Protein Based Nanovaccines via Subcutaneous Immunization

open access: yesAdvanced Functional Materials, EarlyView.
Spider minor ampullate silk protein (MiSp) and retinoic acid (RA) based nanovaccine are capable of eliciting both mucosal and systemic immune responses following subcutaneous administration and demonstrate significant protective effects against CVB3 infection in mice.
Xingmei Qi   +4 more
wiley   +1 more source

Biomimetic Design of Biocompatible Neural Probes for Deep Brain Signal Monitoring and Stimulation: Super Static Interface for Immune Response‐Enhanced Contact

open access: yesAdvanced Functional Materials, EarlyView.
Ultrathin, flexible neural probes are developed with an innovative, biomimetic design incorporating brain tissue‐compatible materials. The material system employs biomolecule‐based encapsulation agents to mitigate inflammatory responses, as demonstrated through comprehensive in vitro and in vivo studies.
Jeonghwa Jeong   +7 more
wiley   +1 more source

A Nearest-Neighbor Based Nonparametric Test for Viral Remodeling in Heterogeneous Single-Cell Proteomic Data [PDF]

open access: yesarXiv, 2020
An important problem in contemporary immunology studies based on single-cell protein expression data is to determine whether cellular expressions are remodeled post infection by a pathogen. One natural approach for detecting such changes is to use non-parametric two-sample statistical tests.
arxiv  

In vitro evaluation of a novel Mg-Sn-Ge ternary alloy for orthopedic applications [PDF]

open access: yesarXiv, 2022
Magnesium (Mg) and its alloys have attracted considerable attention owing to their excellent biodegradable properties and biocompatibility. Novel Mg-Sn-Ge ternary Mg alloys were developed as potential biodegradable materials for orthopedic applications because of their alloying elements naturally present in humans.
arxiv  

IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function

open access: yesClinical Cancer Research, 2016
Purpose: The effectiveness of NK cell infusions to induce leukemic remission is limited by lack of both antigen specificity and in vivo expansion. To address the first issue, we previously generated a bispecific killer engager (BiKE) containing single ...
D. Vallera   +14 more
semanticscholar   +1 more source

Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy

open access: yesAdvanced Functional Materials, EarlyView.
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee   +6 more
wiley   +1 more source

A Beginners Guide to Systems Simulation in Immunology [PDF]

open access: yesarXiv, 2013
Some common systems modelling and simulation approaches for immune problems are Monte Carlo simulations, system dynamics, discrete-event simulation and agent-based simulation. These methods, however, are still not widely adopted in immunology research.
arxiv  

Recombinant Listeria promotes tumor rejection by CD8+ T cell-dependent remodeling of the tumor microenvironment. [PDF]

open access: yes, 2018
Agents that remodel the tumor microenvironment (TME), prime functional tumor-specific T cells, and block inhibitory signaling pathways are essential components of effective immunotherapy.
Barajas, Gonzalo   +12 more
core   +1 more source

Immune Mechanisms in Drug Allergy [PDF]

open access: yes, 2006
Clinicians had suspected for years that drug eruptions were probably mediated by immune mechanisms because their timing suggested sensitization and specific immunologic memory rather than direct toxicity.
Roujeau, Jean-Claude
core   +1 more source

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