Results 111 to 120 of about 3,023,153 (167)

Toxicological testing of cytotoxic drugs (Review)

International Journal of Oncology, 2001
Cytotoxic drugs are a unique therapeutic class of fundamental importance in current antineoplastic chemotherapy. These drugs belong to many chemical and chemotherapeutic classes. They are cytotoxic by design and are able to cause serious dose-limiting adverse effects at therapeutic doses.
P, Colombo, K, Gunnarsson, M, Iatropoulos, M, Brughera   +3 more
openaire   +2 more sources

An approach to avoiding errors in cytotoxic testing

Journal of Immunological Methods, 1973
Abstract It is shown that time and temperature influence the results of cytotoxic assays considerably. In order to avoid errors depending upon these factors a simple modification in counting the cells is recommended.
H, Zimpel, R, Stark, H G, Thiele
openaire   +2 more sources

Cytotoxicity testing of a dentin bonding system

Oral Surgery, Oral Medicine, Oral Pathology, 1985
The cytotoxicity of a newly developed dentin bonding system was examined in African green monkey kidney cells and human embryonic lung cells. A tissue culture agar overlay procedure, a longitudinal study, and a cell replication assay were employed to evaluate cytotoxicity.
T C, Dumsha, R J, Sydiskis
openaire   +2 more sources

Cytotoxicity Testing of Wound-Dressing Materials

Alternatives to Laboratory Animals, 2001
A method was developed for testing the cytotoxicity of various bandage-like wound dressings and gel wound dressings. In this method, the ability of human polymor-phonuclear neutrophils (PMNs) to initiate a respiratory burst after exposure to the various wound dressings is used as a marker of cytotoxicity.
H, Sahlin, H, Nygren
openaire   +2 more sources

In vitro cytotoxicity testing of coladerm membrane

Cell and Tissue Banking, 2001
At present, biodegradable and biocompatible membranes based on collagen and glycosaminoglycans play an important role in substitutive medicine. Modern biomaterials use a chemically modified collagen-based matrix for implants with programmable biodegradability as a substitute of buccal mucosa, skin, cartilage, etc.
J, Vojtassák, D, Bakos, L, Danihel, J, Kristín, D, Böhmer, L, Danisovic, M, Blasko   +6 more
openaire   +2 more sources

The Cytotoxic Test for Leucocyte Antibodies

Vox Sanguinis, 1965
RésuméLes auteurs décrivent une technique pour déterminer les iso‐anticorps cytotoxiques contre les leucocytes humains et présentent une critique concernant les facteurs variables qui peuvent intervenir dans les tests. Ces tests ne requièrent pas d'équipement ou d'habileté spéciale; ils sont rapides à pratiquer et donnent des résultats étonamment ...
C P, Engelfriet, A, Britten
openaire   +2 more sources

Testing thallium cytotoxicity

2021
Talij je metal koji je široko rasprostranjen u okolišu. U povijesti se koristio za liječenje bolesti ljudi (sifilis, malarija, dermatofioza skalpa) potom i kao rodenticid. Zabilježeni su slučajevi trovanja ljudi talijem. Izloženost ljudi taliju se događa ili putem zraka ili putem hrane koja sadrži talij.
Bešić, Erim, Domijan, Ana-Marija, Marjanović Čermak, Ana Marija, Kifer, Domagoj   +3 more
openaire  

Error in cytotoxicity testing by cell lysis

Medical Microbiology and Immunology, 1974
In cytotoxicity testing with murine lymphocytes, cytolysis, i.e. the complete loss of cell contours of the damaged and stained lymphocytes as a result of fluid influx, can cause considerable false negative titre determinations, as demonstrated by time-lapse microphotography. Under the usual test conditions, significant typing errors may be excpeted, if
openaire   +2 more sources

Cytotoxic Food Testing in Alcoholics

Quarterly Journal of Studies on Alcohol, 1974
G A, Ulett, E, Itil, S G, Perry
openaire   +2 more sources

Complement activation induces excessive T cell cytotoxicity in severe COVID-19

Cell, 2022
Jacob Nattermann, Birgit Sawitzki, Markus Ralser   +2 more
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