Results 151 to 160 of about 282,462 (357)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Determination of benchmark concentrations and their statistical uncertainty for cytotoxicity test data and functional in vitro assays

, 2019
A. T. Krebs
openalex   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

In vitro cytotoxicity of superparamagnetic iron oxide nanoparticles on neuronal and glial cells. Evaluation of nanoparticle interference with viability tests [PDF]

, 2015
Carla Costa, Fátima Brandão, Maria João Bessa, Solange Costa, Vanessa Valdiglesias, Gözde Kılıç, Natalia Fernández‐Bertólez, Pedro Quaresma, Eulália Pereira, Eduardo Pásaro, Blanca Laffón, João Paulo Teixeira   +11 more
openalex   +1 more source

Data from Stage 2 Combination Testing of Rapamycin with Cytotoxic Agents by the Pediatric Preclinical Testing Program

, 2023
Peter J. Houghton, Christopher L. Morton, Richard Görlick, Richard B. Lock, Hernán Carol, C. Patrick Reynolds, Min H. Kang, John M. Maris, Stephen T. Keir, E. Anders Kolb, Jianrong Wu, Amy Wozniak, Catherine A. Billups, Larry Rubinstein, Malcolm A. Smith   +14 more
openalex   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Development of On-chip Coculture System for Cytotoxicity Test Using Caco-2 and Hep G2

, 2009
Hiroshi Kimura, Hidenari Nakayama, Takatoki Yamamoto, Yasuyuki Sakai, Teruo Fujii   +4 more
openalex   +2 more sources

Differences of Cytotoxicity of Orthodontic Bands Assessed by Survival Tests inSaccharomyces cerevisiae [PDF]

, 2014
Tatiana Siqueira Gonçalves, Luciane Macedo de Menezes, Luciele Gonzaga Ribeiro, Catieli Gobetti Lindholz, Renata Medina‐Silva   +4 more
openalex   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Cytotoxicity Testing of Dental Materials

Indian Journal Of Science And Technology, 2023
K R Navaneethakrishnan, Sanjey Kumar Prabath Udaya Kumar, M R Murali, T N Sathya, Sangeetha V Naveen, S S Murugan, T S Kumaravel   +6 more
openaire   +1 more source