Results 301 to 310 of about 282,462 (357)

Cytotoxicity Testing of Wound-Dressing Materials

Alternatives to Laboratory Animals, 2001
A method was developed for testing the cytotoxicity of various bandage-like wound dressings and gel wound dressings. In this method, the ability of human polymor-phonuclear neutrophils (PMNs) to initiate a respiratory burst after exposure to the various wound dressings is used as a marker of cytotoxicity. Luminol-amplified chemiluminescence stimulated
H, Sahlin, H, Nygren
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Clonogenic cytotoxicity testing by microdrop encapsulation

Nature, 1993
Cytotoxicity is defined as the in situ measurement of cellular function in response to a toxic substance. Cytotoxicity assays are widely used in drug screening and development research to minimize the number of compounds on which expensive mammalian animal model toxicology studies are performed.
B, Goguen, N, Kedersha
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Cytotoxicity Testing of Tomatine

1998
Glycoalkaloids, e.g. solanine and tomatine are found in potato, tomato and other plants. They are toxic to animals. It is difficult to analyze them in food. We developed a bioassay of tomatine. A combination method of HepG2 cell with a chemiluminescent was more easy to operate and rapid than others.
Daio Kozuka, Shiro Yamashoji, Yukiko Chiba, Kenji Isshiki   +3 more
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Cytotoxicity Testing: Cell Experiments

2011
Screening for new anticancer agents has traditionally been done with in vitro cell culture methods. Even in the genomic era of target-driven drug design, screening for cytotoxic activity is still a standard tool in the search for new anticancer agents, especially if the mode of action of a substance is not yet known.
Renate Grünert, Aron Westendorf, Magdalena Buczkowska, Mareike Hänsch, Sybil Grüunert, Patrick J. Bednarski   +5 more
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Cytotoxicity test and mass spectrometry of IPMC

Electronics and Communications in Japan, 2008
AbstractIonic polymer‐metal composites (IPMC) are promising materials in biomedical actuators and sensors, as they are soft and flexible, thus assuring the safety of the device itself. The purpose of this study is to investigate the biocompatibility of IPMC in in vitro experiments in order to evaluate their applicability in biomedical fields.
Kazuto Takashima, Norihiro Kamamichi, Tohru Yagi, Kinji Asaka, Toshiharu Mukai   +4 more
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Metabolizing systems in cell culture cytotoxicity tests

Xenobiotica, 1988
1. The addition of 9000 g supernatant of rat liver homogenate (S9) or rat liver microsomal fractions to a cytotoxicity test system using BCL-D1 cells has been investigated. 2. The choice of culture medium influenced the intrinsic cytotoxicity of the metabolising system to the BCL-D1 cells.
D J, Benford, H J, Reavy, S A, Hubbard
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Cytotoxicity testing of a dentin bonding system

Oral Surgery, Oral Medicine, Oral Pathology, 1985
The cytotoxicity of a newly developed dentin bonding system was examined in African green monkey kidney cells and human embryonic lung cells. A tissue culture agar overlay procedure, a longitudinal study, and a cell replication assay were employed to evaluate cytotoxicity.
T C, Dumsha, R J, Sydiskis
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In vitro cytotoxicity testing of coladerm membrane

Cell and Tissue Banking, 2001
At present, biodegradable and biocompatible membranes based on collagen and glycosaminoglycans play an important role in substitutive medicine. Modern biomaterials use a chemically modified collagen-based matrix for implants with programmable biodegradability as a substitute of buccal mucosa, skin, cartilage, etc.
J, Vojtassák, D, Bakos, L, Danihel, J, Kristín, D, Böhmer, L, Danisovic, M, Blasko   +6 more
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SOP/DTX/155 Cytotoxicity Tests

1980
Since chemicals may interact with cells in a variety of ways, the criteria for defining a toxic concentration depends on the technique used to measure toxicity. Thus toxicity can be expressed in terms of the doses of chemical which inhibit colony formation, cause detachment of cells from glass or plastic, inhibit DNA, RNA or protein synthesis, cause ...
I. P. Sword, Ritchie Thomson
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Error in cytotoxicity testing by cell lysis

Medical Microbiology and Immunology, 1974
In cytotoxicity testing with murine lymphocytes, cytolysis, i.e. the complete loss of cell contours of the damaged and stained lymphocytes as a result of fluid influx, can cause considerable false negative titre determinations, as demonstrated by time-lapse microphotography. Under the usual test conditions, significant typing errors may be excpeted, if
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