Results 321 to 330 of about 435,610 (360)
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The Cytotoxic Test for Leucocyte Antibodies
Vox Sanguinis, 1965RésuméLes auteurs décrivent une technique pour déterminer les iso‐anticorps cytotoxiques contre les leucocytes humains et présentent une critique concernant les facteurs variables qui peuvent intervenir dans les tests. Ces tests ne requièrent pas d'équipement ou d'habileté spéciale; ils sont rapides à pratiquer et donnent des résultats étonamment ...
C. P. Engelfriet, A. Britten
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An approach to avoiding errors in cytotoxic testing
Journal of Immunological Methods, 1973Abstract It is shown that time and temperature influence the results of cytotoxic assays considerably. In order to avoid errors depending upon these factors a simple modification in counting the cells is recommended.
H.-G. Thiele, H. Zimpel, R. Stark
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Cytotoxicity Testing of Tomatine
1998Glycoalkaloids, e.g. solanine and tomatine are found in potato, tomato and other plants. They are toxic to animals. It is difficult to analyze them in food. We developed a bioassay of tomatine. A combination method of HepG2 cell with a chemiluminescent was more easy to operate and rapid than others.
Daio Kozuka +3 more
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Toxicological testing of cytotoxic drugs (Review)
International Journal of Oncology, 2001Cytotoxic drugs are a unique therapeutic class of fundamental importance in current antineoplastic chemotherapy. These drugs belong to many chemical and chemotherapeutic classes. They are cytotoxic by design and are able to cause serious dose-limiting adverse effects at therapeutic doses.
M Iatropoulos +3 more
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Controlled Study of the Cytotoxic Food Test
JAMA: The Journal of the American Medical Association, 1975The cytotoxic food test was not found to be an accurate method for diagnosing atopic reactions to foods. Claims that the test correlated with other untoward reactions to foods (eg, headache, diarrhea, fatigue) could not be corroborated. The test itself is time-consuming, dependent on subjective interpretation, and inconsistent in results when ...
Phil Lieberman +4 more
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Cytotoxicity Testing of Wound-Dressing Materials
Alternatives to Laboratory Animals, 2001A method was developed for testing the cytotoxicity of various bandage-like wound dressings and gel wound dressings. In this method, the ability of human polymor-phonuclear neutrophils (PMNs) to initiate a respiratory burst after exposure to the various wound dressings is used as a marker of cytotoxicity. Luminol-amplified chemiluminescence stimulated
Herman Sahlin, Håkan Nygren
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Error in cytotoxicity testing by cell lysis [PDF]
Medical Microbiology and Immunology, 1974 In cytotoxicity testing with murine lymphocytes, cytolysis, i.e. the complete loss of cell contours of the damaged and stained lymphocytes as a result of fluid influx, can cause considerable false negative titre determinations, as demonstrated by time-lapse microphotography. Under the usual test conditions, significant typing errors may be excpeted, if
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Clonogenic cytotoxicity testing by microdrop encapsulation
Nature, 1993Cytotoxicity is defined as the in situ measurement of cellular function in response to a toxic substance. Cytotoxicity assays are widely used in drug screening and development research to minimize the number of compounds on which expensive mammalian animal model toxicology studies are performed.
Nancy Kedersha, Blane Goguen
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Cytotoxicity testing of a dentin bonding system
Oral Surgery, Oral Medicine, Oral Pathology, 1985The cytotoxicity of a newly developed dentin bonding system was examined in African green monkey kidney cells and human embryonic lung cells. A tissue culture agar overlay procedure, a longitudinal study, and a cell replication assay were employed to evaluate cytotoxicity.
Thom C. Dumsha, Robert J. Sydiskis
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Serial dilution microchip for cytotoxicity test [PDF]
Journal of Micromechanics and Microengineering, 2004 Today's pharmaceutical industry is facing challenges resulting from the vast increases in sample numbers produced by high-throughput screening (HTS). In addition, the bottlenecks created by increased demand for cytotoxicity testing (required to assess compound safety) are becoming a serious problem.
Young Kyung Lee +6 more
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