Results 61 to 70 of about 431,582 (362)

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

FEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr, Klaus Mayer, Raffael Schaffrath, Johannes Buchner, Ulrich Brinkmann   +4 more
wiley   +1 more source

Calcium carbonate-calcium phosphate mixed cement compositions for bone reconstruction [PDF]

, 2006
The feasibility of making calcium carbonate-calcium phosphate (CaCO3-CaP) mixed cements, comprising at least 40 % (w/w) CaCO3 in the dry powder ingredients, has been demonstrated.
Arnaud, Atlan, Blom, Bohic, Bohner, Bohner, Braye, Brecevic, Brown, Cazalbou, Chiroff, Collins, Combes, Constantz, Daculsi, Damien, De Maeyer, dos Santos, Elliott, Fernandez, Fontaine, Ginebra, Guillemin, Hatim, Heughebaert, Heughebaert, Huffman, Ikenaga, Jamali, Khairoun, Kon, Larsen, Legeros, Lucas, Maeda, Meldrum, Mirtchi, Mirtchi, Mosmann, Nillson, Ohura, Oyane, Parish, Penel, Piattelli, Rawlings, Reddy, Rey, Rey, Rey, Rey, Sabbides, Souyris, Tofighi, Vilamitjana-Amédée, Walsh   +55 more
core   +2 more sources

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

FEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine, Matteo Mucci, Antonio Recchiuti, Domenico Mattoscio   +3 more
wiley   +1 more source

In Vitro Tests of FDM 3D-Printed Diclofenac Sodium-Containing Implants

Molecules, 2020
One of the most promising emerging innovations in personalized medication is based on 3D printing technology. For use as authorized medications, 3D-printed products require different in vitro tests, including dissolution and biocompatibility ...
Petra Arany, Ildikó Papp, Marianna Zichar, Máté Csontos, János Elek, Géza Regdon, István Budai, Mónika Béres, Rudolf Gesztelyi, Pálma Fehér, Zoltán Ujhelyi, Gábor Vasvári, Ádám Haimhoffer, Ferenc Fenyvesi, Judit Váradi, Vecsernyés Miklós, Ildikó Bácskay   +16 more
doaj   +1 more source

In vitro assessment of cytotoxicity of giomer on human gingival fibroblasts [PDF]

, 2009
Root coverage on restored root surfaces has been considered as a challenging issue. The evaluation of cytotoxic effects of restorative materials is a fundamental requirement for sustaining the cell attachment and the clinical success of root coverage ...
Farajnia, S., Johnson, A., Kimyai, S., Mohammadnejad, L., Nejatian, T., Pourabbas, R.   +5 more
core   +1 more source

A peroxisome proliferator-activated receptor-δ agonist provides neuroprotection in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease [PDF]

, 2013
Copyright © 2013 IBRO. Published by Elsevier Ltd.
Barak, Basu-Modak, Bishop-Bailey, Breidert, Chen, Chen, Chopra, Ciesielska, Czlonkowska, Dauer, Dehmer, Delerive, Desvergne, Devchand, Dong, Escribano, H.L. Martin, Hsieh, Hébert, Iwashita, Jackson-Lewis, K. Sathe, Kalinin, Kreisler, Long-Smith, Luquet, M.C. Nelson, Martin, McGeer, Mogi, Mogi, Nicolakakis, Niino, Nuber, P. Teismann, Pascal, Polak, R.B. Mounsey, R.M. Evans, Ricote, S. Mustafa, Santos, Schintu, Shearer, Shi, Storer, Sznaidman, Takahashi, Teismann, Tian, Wang, West, Wu, Xu, Xu, Yacoub, Yi   +56 more
core   +1 more source

Pulsed vacuum arc deposition of nitrogen-doped diamond-like coatings for long-term hydrophilicity of electrospun polycaprolactone scaffolds [PDF]

arXiv, 2022
The surface hydrophobicity of poly($\epsilon$-caprolactone) electrospun scaffolds prevents their interactions with cells and tissue integration. Plasma treatment of the scaffolds enhances their hydrophilicity. However, the hydrophobicity of scaffolds is restored in about 30 days.
arxiv  

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Cytotoxicity and Mineralization Activity of Calcium Silicate-Based Root Canal Sealers Compared to Conventional Resin-Based Sealer in Human Gingival Fibroblast Cells

International Journal of Dentistry, 2023
Background. Root canal obturation is performed by gutta-percha cones and sealer. Therefore, these materials, specially sealers, must be biocompatible.
Mohammad Shokrzadeh, Farzaneh Sadat Motafeghi, Anahita Lotfizadeh, Mohammad Ghorbani, Azam Haddadi Kohsar   +4 more
doaj   +1 more source

Cytotoxic and Mutagenic Effects and cell Viability of Polybia sericea Social Wasp Venom (Hymenoptera: Vespidae) [PDF]

The venom of social wasps can be a natural promising product for the development of drugs, since in recent decades studies have investigated its antimicrobial potential, anti-inflammatory, antioxidant, anticarcinogenic, among others for its future ...
Antonialli-Junior, William Fernando, Cardoso, Claudia Andrea Lima, Castilho, Pamella Fukuda de, Castro, David Tsuyoshi Hiramatsu de, Castro, Thiago Luis Aguayo de, Oliveira, Kelly Mari Pires de, Santos, Edson Lucas dos, Soares, Eva Ramona Pereira, Torres, Viviana Oliveira   +8 more
core   +2 more sources