Results 61 to 70 of about 445,868 (362)

In vitro assessment of cytotoxicity of giomer on human gingival fibroblasts [PDF]

, 2009
Root coverage on restored root surfaces has been considered as a challenging issue. The evaluation of cytotoxic effects of restorative materials is a fundamental requirement for sustaining the cell attachment and the clinical success of root coverage ...
Farajnia, S., Johnson, A., Kimyai, S., Mohammadnejad, L., Nejatian, T., Pourabbas, R.   +5 more
core   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Dysregulation of microtubule stability impairs morphofunctional connectivity in primary neuronal networks [PDF]

, 2017
Functionally related neurons assemble into connected networks that process and transmit electrochemical information. To do this in a coordinated manner, the number and strength of synaptic connections is tightly regulated.
Jacobine Kuijlaars, Jan R. Detrez, Jean-Pierre Timmermans, Marlies Verschuuren, Peter Verstraelen, Rony Nuydens, Winnok H. De Vos, Winnok H. De Vos   +7 more
core   +2 more sources

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Avaliação da biocompatibilidade de vidro e vitrocerâmica do sistema SNCP (SiO2-Na2O-CaO-P2O5)

Química Nova, 2012
This article reports research results related to bioactivity and cytotoxicity tests using neutral red uptake method for glass powders and bulk glass ceramics belonging to the SNCP (SiO2-Na2O-CaO-P2O5) system.
Karoline Bastos Mundstock, Antonio Pedro Novaes de Oliveira, Dachamir Hotza, Sizue Ota Rogero   +3 more
doaj   +1 more source

Cytotoxicity and Mineralization Activity of Calcium Silicate-Based Root Canal Sealers Compared to Conventional Resin-Based Sealer in Human Gingival Fibroblast Cells

International Journal of Dentistry, 2023
Background. Root canal obturation is performed by gutta-percha cones and sealer. Therefore, these materials, specially sealers, must be biocompatible.
Mohammad Shokrzadeh, Farzaneh Sadat Motafeghi, Anahita Lotfizadeh, Mohammad Ghorbani, Azam Haddadi Kohsar   +4 more
doaj   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

A peroxisome proliferator-activated receptor-δ agonist provides neuroprotection in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease [PDF]

, 2013
Copyright © 2013 IBRO. Published by Elsevier Ltd.
Barak, Basu-Modak, Bishop-Bailey, Breidert, Chen, Chen, Chopra, Ciesielska, Czlonkowska, Dauer, Dehmer, Delerive, Desvergne, Devchand, Dong, Escribano, H.L. Martin, Hsieh, Hébert, Iwashita, Jackson-Lewis, K. Sathe, Kalinin, Kreisler, Long-Smith, Luquet, M.C. Nelson, Martin, McGeer, Mogi, Mogi, Nicolakakis, Niino, Nuber, P. Teismann, Pascal, Polak, R.B. Mounsey, R.M. Evans, Ricote, S. Mustafa, Santos, Schintu, Shearer, Shi, Storer, Sznaidman, Takahashi, Teismann, Tian, Wang, West, Wu, Xu, Xu, Yacoub, Yi   +56 more
core   +1 more source

Investigating bacteriophages targeting the opportunistic pathogen Acinetobacter baumannii [PDF]

, 2020
The multi-drug resistance of the opportunistic pathogen Acinetobacter baumannii is of growing concern, with many clinical isolates proving to be resistant to last resort as well as front line antibiotic treatments.
Christie, Gabrielle S., Dowson, Christopher G., Leungtongkam, Udomluk, Millard, Andrew D., Moat, John, Sagona, Antonia P., Sitthisak, Sutthirat, Smith, Sophie, Styles, Kathryn, Thummeepak, Rapee, Wellington, Elizabeth M. H.   +10 more
core   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source