Results 31 to 40 of about 833,670 (244)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Etude Sur la Stratégie et le Programme D'appui à la Société Civile Burundaise [PDF]

open access: yes, 2002
The author study's strategies and programs to build civil society in ...
Christophe Sebudandi, Gérard Nduwayo
core  

Enfants-soldats au Nigeria : les romanciers témoignent [PDF]

open access: yes, 2011
During an interview, Ishmael Beah, conscripted in Sierra Leone when he was 13, testified to the fact that the rights of child‐soldiers were constantly violated.
Ugochukwu, Francoise
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Turkey's EU Membership Process: Prospects and Challenges. College of Europe EU Diplomacy Paper 5/2010 [PDF]

open access: yes, 2010
Lecture by H.E. Mr Egemin Bagıs, Turkey's Minister for EU Affairs and Chief Negotiator, at the College of Europe in Bruges on 3 February ...
Bagıs, Egemen.
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A injunção da participação no campo ambiental ou a questão da incorporação dos "públicos" nos espaços de discussão

open access: yesSociologias, 2014
Quer se fale de "virada" ou de "imperativo" deliberativo, a democracia participativa está no bojo do tratamento dos problemas de meio ambiente, envolvendo o público.
Jean-Paul Billaud
doaj   +3 more sources

The use of nuclear data in the field of nuclear fuel recycling

open access: yesEPJ Web of Conferences, 2017
AREVA NC La Hague facility is the first step of the nuclear fuel recycling process implemented in France. The processing of the used fuel is governed by high standards of criticality-safety, and strong expectations on the quality of end-products.
Martin Julie-Fiona   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

On the Trans-Siberian with Sylvester Stallone: National Identity and Brand Identity in Post-socialist Russia

open access: yesQuaestio Rossica, 2014
В этой короткой статье мы рассматриваем, как при создании брендовой идентичности в постсоветской России происходит обращение к патриотическим чувствам потребителей. В рамках темы исследование ограничивается сферой алкогольной продукции.
Graham Roberts
doaj   +1 more source

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