Results 51 to 60 of about 1,334,914 (244)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Stress and defense responses in plant secondary metabolites production

Biological Research, 2019
In the growth condition(s) of plants, numerous secondary metabolites (SMs) are produced by them to serve variety of cellular functions essential for physiological processes, and recent increasing evidences have implicated stress and defense response ...
T. Isah
semanticscholar   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The use of nuclear data in the field of nuclear fuel recycling

EPJ Web of Conferences, 2017
AREVA NC La Hague facility is the first step of the nuclear fuel recycling process implemented in France. The processing of the used fuel is governed by high standards of criticality-safety, and strong expectations on the quality of end-products.
Martin Julie-Fiona, Launay Agnès, Grassi Gabriele, Binet Christophe, Lelandais Jacques, Lecampion Erick   +5 more
doaj   +1 more source

On the Trans-Siberian with Sylvester Stallone: National Identity and Brand Identity in Post-socialist Russia

Quaestio Rossica, 2014
В этой короткой статье мы рассматриваем, как при создании брендовой идентичности в постсоветской России происходит обращение к патриотическим чувствам потребителей. В рамках темы исследование ограничивается сферой алкогольной продукции.
Graham Roberts
doaj   +1 more source

The compelling link between physical activity and the body's defense system

Journal of Sport and Health Science, 2018
Highlights • Acute exercise is an immune system adjuvant that improves defense activity and metabolic health.• Data support a clear inverse relationship between moderate exercise training and illness risk.• Exercise training has an anti-inflammatory ...
D. Nieman, Laurel M. Wentz
semanticscholar   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Predicting Is Not Explaining: Targeted Learning of the Dative Alternation

Journal of Causal Inference, 2016
Corpus linguists dig into large-scale collections of texts to better understand the rules governing a given language. We advocate for ambitious corpus linguistics drawing inspiration from the latest developments of semiparametrics for a modern targeted ...
Chambaz Antoine, Desagulier Guillaume
doaj   +1 more source