Results 51 to 60 of about 847,178 (247)

Papers prepared for the Colloquium "Working for Europe: Perspectives on the EU 50 Years after the Treaties of Rome" [PDF]

open access: yes, 2007
The Chamber of Representatives of the Belgian Parliament asked the permanent professors of the College of Europe to write brief papers for a conference organized in honour of the 50th anniversary of the Treaty of Rome.
Chang, Michele   +3 more
core  

The Second Anniversary of the Constitutionalisation of the French Charter for the Environment: Constitutional and Environmental Implications [PDF]

open access: yes, 2008
The former French president J. Chirac will most likely be remembered for his international standing against the US and domestically, within France, for having initiated a major ‘bill of rights’, the Charter for the Environment, and for its ...
Marrani, David
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Control measures to prevent the increase of paratuberculosis prevalence in dairy cattle herds: an individual-based modelling approach

open access: yesVeterinary Research, 2018
Paratuberculosis, a gastrointestinal disease caused by Mycobacterium avium subsp. paratuberculosis (Map), can lead to severe economic losses in dairy cattle farms.
Guillaume Camanes   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Advancing protection for the rights of women and children in Mali: the ruling of the african court of human and peoples’ rights against the provisions of the family code [PDF]

open access: yes, 2018
The paper aims at highlighting the main contents and features of the decision Association pour le Progrèset la Défense des Droits des Femmes Maliennes et al v.Republic of Mali of the African Court on Human and Peoples’ Rights.
Giacomini, Giada
core  

Fine and ultrafine particle number and size measurements from industrial combustion processes : primary emissions field data [PDF]

open access: yes, 2020
This study is to our knowledge the first to present the results of on-line measurements of residual nanoparticle numbers downstream of the flue gas treatment systems of a wide variety of medium- and large-scale industrial installations.
Blondeau, J.   +9 more
core   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

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