Results 51 to 60 of about 833,670 (244)

Power, Techno-economics, and Transatlantic Relations in 1987-1999 [PDF]

, 2005
This essay suggests that in 1987-1999 European elites, in their efforts of asymmetric balancing against the United States hegemony, decided to trade-off military capability for economic competitiveness.
Lungu, Sorin.
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Heterogenous within-herd seroprevalence against epizootic hemorrhagic disease virus type 8 (EHDV-8) after massive virus circulation in cattle in France, 2023

Frontiers in Veterinary Science
Background and objectivesThe emergence of Epizootic Hemorrhagic Disease Virus-8 (EHDV-8) in mainland France in 2023 led to thousands of clinical outbreaks in cattle herds and likely led to the natural immunization of a large number of animals.
Corinne Anthonioz, Yann Abadie, Elodie Reversat, Annie Lafargue, Manon Delalande, Thierry Renaudineau, Laurent Delobel, Nathalie Verdeille, David Ngwa-Mbot, Kristel Gache, Emmanuel Garin, Fabien Corbiere   +11 more
doaj   +1 more source

Control measures to prevent the increase of paratuberculosis prevalence in dairy cattle herds: an individual-based modelling approach

Veterinary Research, 2018
Paratuberculosis, a gastrointestinal disease caused by Mycobacterium avium subsp. paratuberculosis (Map), can lead to severe economic losses in dairy cattle farms.
Guillaume Camanes, Alain Joly, Christine Fourichon, Racem Ben Romdhane, Pauline Ezanno   +4 more
doaj   +1 more source

Les Organisations de la Société Civile et la Lutte Contre la Pauvreté en Afrique Subsaharienne [PDF]

, 2004
The paper presents the role played by civil society organisations to bring down the ...
Aurélien C. Atidegla, Celestin Hounkpe, Elisabeth Paul, Gregor Stangherlin, Latifou Yessoufou, Magloire Cossou, Marc Labie, Marc Poncelet, Marthe Nyssen, Mathieu Soglonou, Pascal Wele, Simon-Narcisse Tomety   +11 more
core  

Des horizons qui se resserrent: les politiques de défense conservatrices dans un monde en plein bouleversement [PDF]

, 2000
La décennie Mulroney présente des conditions qui ont amené le gouvernement conservateur à modifier considérablement ses orientations de politiques et, à cet égard, le secteur de la défense a probablement été plus affecté que tout autre. Le gouvernement a
Ripsman, Norrin M.
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

La politique de défense est-elle a-politique ? [PDF]

, 2007
Au-delà du goût pour les paradoxes, l’interrogation sur le caractère a-politique de la politique de défense prend tout son sens et sa pertinence, si l’on s’attache à la sphère de la politique électorale entendue comme compétition et lutte pour le pouvoir.
Irondelle, Bastien
core  

Delenda est haec Carthago: the Ostend company as a problem of European great power politics (1722-1727) [PDF]

, 2015
The Ostend Company (1722-1731) is a symbol of present-day Belgium’s strangling by European Great Power politics in the Ancien Régime, and more specifically of the limitations imposed on the Southern Netherlands by the Dutch Republic in 1648.
Dhondt, Frederik
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source