Results 111 to 120 of about 835,613 (245)

Sepsis Induces Long‐Term Muscle and Mitochondrial Dysfunction due to Autophagy Disruption Amenable by Urolithin A

Journal of Cachexia, Sarcopenia and Muscle
Background Sepsis survivors often experience sustained muscle weakness, leading to physical disability, with no pharmacological treatments available.
Alexandre Pierre, Raphael Favory, Benoit Brassart, Claire Bourel, Raphael Romien, Sylvain Normandin, Arthur Dubech, Claire Vincent, Jeremy Lemaire, Gaelle Grolaux, Ophelie Not, Frederic Wallet, Frederic Daussin, Eric Boulanger, Arthur Durand, Marie Frimat, Alina Ghinet, Michael Howsam, William Laine, Philippe Marchetti, Jerome Kluza, Estelle Chatelain, Jimmy Vandel, Nicolas Barois, Valerie Montel, Bruno Bastide, Sebastien Preau, Steve Lancel   +27 more
doaj   +1 more source

Les déterminants nominaux aspectuels

, 1996
International audienceNous nous intéressons à la catégorie de l'aspect et aux différents moyens syntaxiques et lexicaux qu'un locuteur français peut employer pour exprimer "a manière dont un événement se développe à travers le cadre du temps où un ...
Buvet, Pierre-André, Lim, Jung-Hae
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Does external openness influence the infant mortality rates? An econometric investigation for the Chinese provinces. [PDF]

During the last decades, China has achieved some remarkable results in improving the health status of its population. Since the end of the seventies, it has engaged in a process of large reforms in integrating with the global economy.
Jacky MATHONNAT, Martine AUDIBERT, Yu CHEN   +2 more
core  

Freins et incitations au développement de l’agriculture biologique en France : une analyse à plusieurs niveaux [PDF]

, 2013
Not ...
Allaire, Gilles, Cahuzac, Eric, Garapin, Alexis, Latruffe, Laure, Lemarié, Stéphane, Nauges, Céline, Poméon, Thomas   +6 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Détermination automatique de la taille du pas de temps pour les schémas implicites en dynamique non linéaireAutomatic time-stepping algorithms for implicit schemes in non-linear dynamics [PDF]

Mécanique & Industries, 2002
openaire   +1 more source

Dropout, School Performance and Working while in School : An Econometric Model with Heterogeneous Groups [PDF]

We develop an econometric model where the determinants of work while in school, dropout and academic grades are set in the context of two types of high school students: those who favor schooling and those who are more inclined to access rapidly the labor
Claude Montmarquette, Marcel Dagenais, Nathalie Viennot-Briot   +2 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source