Results 121 to 130 of about 798,630 (244)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Environmental Performance of Canadian Pulp and Paper Plants: Why Some Do Well and Others Do Not ? [PDF]
It is generally recognized that firms face both internal and external pressure to improve their environmental performance. However, few studies have attempted to delineate the importance of those various sources of pressure as firms' managers themselves ...
Benoit Laplante +2 more
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Analyse macro-économétrique du chômage dans les pays de l’UEMOA
Revue Internationale des Économistes de Langue FrançaiseL’objectif : cet article vise à évaluer les déterminants macroéconomiques du chômage dans les pays de l’UEMOA, en mettant un accent particulier sur les chocs pluviométriques. Conception/méthodologie/approche : L’utilisation des données sous régionales
Ousmane Mariko, Mohamed Niaré
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Divulgations environnementales : quel référentiel pour quelles fins ?
, 2015 International audienceGRI offers an international reference to firm’s stakeholders interested in social and environmental disclosures. However these disclosures target first and foremost investors, especially for listed firms.
Allirol, Béatrice, Dumontier, Pascal
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Cereal Supplies in Rural Families of the Senegalese Groundnut Basin. Who is Responsible for Meeting Family Food Needs? [PDF]
In the traditional operation of production-consumption groups in rural areas of Senegal, the group chief, or Borom njël, has a social duty to make sure family food needs are met. His ability to do this is supported by certain social rules governing these
Benoit-Cattin, M., Sakho-Jimbira, M.S.
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Les déterminants de la persistance de l’analphabétisme en Côte d’Ivoire
Mu Kara SaniCet article sur les déterminants de la persistance de l’analphabétisme en Côte d’Ivoire est une étude menée sur différents sites sélectionnés au sud, à l’ouest, au centre et au nord du pays. Des documents sont d’abord analysés.
Krouélé TOURE +2 more
doaj