Results 191 to 200 of about 146,774 (240)

Targeting G1-S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors. [PDF]

Nature
Singh S, Gleason CE, Fang M, Laimon YN, Khivansara V, Xie S, Durmaz YT, Sarkar A, Ngo K, Savla V, Li Y, Abu-Remaileh M, Li X, Locquet MA, Tuladhar B, Odeh R, Hamkins-Indik F, He D, Membreno MW, Nosrati M, Gushwa NN, Leung SSF, Fraga-Walton B, Hernandez L, Baldomero MP, Lent BM, Spellmeyer D, Luna JF, Hoang D, Gritsenko Y, Chand M, DeMart MK, Metobo S, Bhatt C, Shapiro JA, Yang K, Dupper NJ, Bockus AT, Fang J, Bambal R, Cremin P, Doench JG, Aggen JB, Liu LF, Levin B, Wang EW, Vendrell I, Fischer R, Kessler B, Gokhale PC, Signoretti S, Spektor A, Kreatsoulas C, Evangelista M, Singh R, Earp DJ, Nijhawan D, Garcia PD, Oser MG.   +58 more
europepmc   +1 more source

A translational multimodal machine‐learning prototype predicting valproate response in epilepsy treatment

Epilepsia, EarlyView.
Abstract Objective Epilepsy affects ~1% of the global population and often requires lifelong antiseizure medication (ASM) therapy. Valproic acid (VPA) is a commonly prescribed first‐line ASM, yet only approximately half of patients achieve sustained seizure freedom. Treatment selection remains largely empirical.
Simeon Platte, Afsheen Kumar, Giorgia Guerini, Massimo Pandolfo, Denise Haslinger, Colin B. Josephson, Guillermo Delgado‐García, Navprabhjot Kaur, Michaela‐Pauline Lux, Heiko Stempfle, Chantal Depondt, Reetta Kälviäinen, Felix Rosenow, Sophie von Brauchitsch, Karl Martin Klein, Andreas G. Chiocchetti   +15 more
wiley   +1 more source

A prognostic model for gastric cancer based on histamine-associated prognostic genes. [PDF]

Hereditas
Zhang Y, Liu N, Dong X, Li Y, Geng J, Li Y.   +5 more
europepmc   +1 more source

Web-Based Personalized Machine Learning Recommendations to Enhance Shared Decision-Making in Prostate-Specific Antigen Screening: Randomized Controlled Trial. [PDF]

JMIR Aging
Lin YT, Huang YC, Liu CK, Cho HY, Chen M.   +4 more
europepmc   +1 more source

Co-occurrence of nephrocalcinosis and nephrolithiasis in feline kidneys. [PDF]

J Vet Intern Med
Hengtrakul N, Furrow E, Toth F, Borofsky M, Lulich JP.   +4 more
europepmc   +1 more source

Pharmacokinetics and Safety of Single and Multiple Doses of Molnupiravir in Healthy Male Chinese Adults: An Open-Label, Fixed Sequence, Phase 1 Study. [PDF]

Clin Transl Sci
Zhu J, Zhang D, Liu Z, Yan B, Zang Y, Zhao W, Sun F, Maas BM, Cheng MH, Stoch SA, Li H.   +10 more
europepmc   +1 more source

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Effects of D-004, antioxidant and antiflammatory substances on testosterone-induced prostate hyperplasia in rats

Oxidants and Antioxidants in Medical Science, 2013
The aim of this study was to investigate the possible contribution of the anti-inflammatory and antioxidant effects of D-004, the lipid extract of the royal palm (Roystonea regia) fruits, on testosterone-induced prostate hyperplasia (PH) in rats. Rats were randomized into seven groups: a negative control and six groups were injected subcutaneously with
Ambar Yera, Yohani Guerra, Sonia Despaigne, Rosa Ferreiro, Vivian Cuevas   +4 more
openaire   +1 more source