Results 131 to 140 of about 14,369,746 (295)

Dose-response effects of d-amphetamine on effort-based decision-making and reinforcement learning. [PDF]

Neuropsychopharmacology, 2021
Soder HE, Cooper JA, Lopez-Gamundi P, Hoots JK, Nunez C, Lawlor VM, Lane SD, Treadway MT, Wardle MC.   +8 more
europepmc   +1 more source

Facilitation of appetitive Pavlovian conditioning by d-amphetamine in the shell, but not the core, of the nucleus accumbens

, 2003
The effects of postsession d-amphetamine within subregions of the ventral and dorsal striatum on appetitive Pavlovian learning were assessed. Rats acquired a conditioned approach response on presentation of a stimulus predictive of 10% sucrose solution ...
Setzu, E, Setzu, E., Phillips, G.D., Hitchcott, P.K., Phillips, G. D., HITCHCOTT, PAUL KENNETH   +5 more
core   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Asians compared to Whites show increased response to d-amphetamine on select subjective and cardiovascular measures

, 2016
ObjectiveIdentifying factors that moderate subjective response to stimulants is important for understanding individuals at risk for abusing these drugs.
Goldenson, Nicholas I, Guillot, Casey R, Pang, Raina D, Kirkpatrick, Matthew G, Leventhal, Adam M   +4 more
core   +1 more source

Signal detection and characterisation of a novel drug–drug interaction between methadone and a synthetic cannabinoid receptor agonist

British Journal of Pharmacology, EarlyView.
Background and Purpose Little is known about how synthetic cannabinoid receptor agonist (SCRA) co‐use with other psychoactive substances may exacerbate risk of death. This study aimed to characterise the polypharmacy of deaths where SCRAs were detected at post‐mortem, investigate the cardiotoxicity of SCRAs and probe their inhibition of human ether‐a ...
Kirsten L. Rock, Louise M. Hesketh, Hongwei Cheng, Shuoqi Chen, Simon Hudson, Graeme Henderson, Jules C. Hancox, Michael J. Shattock, Michael J. Curtis, Caroline S. Copeland   +9 more
wiley   +1 more source

Sibling Coping Provision, Negative Life Events, and Substance Use

Family Relations, EarlyView.
ABSTRACT Objective This study examined sibling coping provision as a moderator between negative life events and emerging adult substance use. Background Greater frequency of negative life events can increase substance use in emerging adulthood. As siblings often use their relationship to cope with stress, the ways in which emerging adults interact with
Derek D. Morgan, Sarah Killoren, Christy R. Rogers   +2 more
wiley   +1 more source

Antiinflammatory and Antipyretic Activities of Stem Extract and Fractions of Telfairia occidentalis in Rodents

Biology, Medicine & Natural Product Chemistry
Telfairia occidentalis Hook (Family-Cucurbitaceae) is a vegetable employed in Ibibio traditional medicine for the treatment of various diseases such as malaria and fever among others.
Jude E Okokon, Chinyelu C. Osigwe, Uwaeme Ugonma Florence, Ukeme Essien Andrew   +3 more
doaj   +1 more source

Wellbeing of trans and gender‐diverse people with HIV in the United Kingdom: Results from Positive Voices 2022

HIV Medicine, EarlyView.
Abstract Objectives This national cross‐sectional observational study aimed to assess mental health, quality of life, supportive network, experiences of HIV‐related stigma in healthcare and unmet service need among trans and gender‐diverse people with HIV, compared to cisgender people with HIV.
H. Kitt, C. Kelly, A. Aghaizu, M. Ross, F. C. Lampe, C. J. Smith, V. Martin, C. Humphreys, A. Brown, A. Sparrowhawk, M. Kall, J. Sewell, E. Wainwright, V. Delpech, G. Davis, A. Farah, A. Fasanya, A. J. Rodger, T. Đuretić, PV2022 Study Group   +19 more
wiley   +1 more source

STUDIES ON THE ANALGESIC ACTIVITY OF THE AMPHETAMINE ISOMERS IN MICE

, 1982
Differences in the behavioral effects of the amphetamine isomers have been well documented and are believed to stem from the differential actions of the isomers on central biogenic amine systems.
TOCCO, DONALD ROBERT
core   +1 more source