Results 141 to 150 of about 13,512,755 (196)
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Vasoconstriction and D-Amphetamine-Induced Hypothermia
International Journal of Neuroscience, 1981The hypothermic effect of d-amphetamine was investigated in rats in which vasoconstriction or vasodilation was induced by pharmacological agents: aramine as vasoconstrictor and neprasol as vasodilator. The d-amphetamine-induced hypothermia was enhanced by both drugs among rats kept at 4 degrees C, and both drugs were unable to modify the d-amphetamine ...
S, Yehuda, R L, Carasso, Y, Ben-Uriah
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The use of d-amphetamine with hyperkinetic children
Psychopharmacologia, 1971The effects of short-term treatment of dextroamphetamine on hyperkinetic children were investigated on twenty children who were enrolled in a normal school setting. The study was carried out double-blind. Students were evaluated medically, psychiatrically, neurologically, and administered psychological testing consisting of the Wechsler Intelligence ...
R J, Finnerty, J J, Soltys, J O, Cole
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Potentiation of morphine analgesia by d-amphetamine
Psychopharmacology, 1986Rats were trained to escape from aversive electrical brain stimulation delivered to the mesencephalic reticular formation (MRF). The threshold for this escape behavior was determined by a modification of the classic psychophysical method of limits. Escape thresholds were determined after the administration of morphine alone, d-amphetamine alone, and ...
S, Sasson, E M, Unterwald, C, Kornetsky
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The effects of d-amphetamine on risk taking
Psychopharmacologia, 1962The effect of d-amphetamine on the risk-taking behavior of penitentiary inmates was investigated, utilizing a gambling situation involving cigarettes. The experimental situation consisted of choices between alternative gambles involving different amounts of risk. The 29 men served as their own controls, with the number of high-risk choices made by each
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Protection against d-amphetamine toxicity
The American Journal of Emergency Medicine, 1990The efficacy of diazepam, haloperidol, propranolol, and yohimbine in antagonizing the toxic manifestations of d-amphetamine were studied in rats. In the control group of animals given 75 mg/kg intraperitoneal (ip) d-amphetamine, 95% developed seizures, and 100% died in mean times of 12.6 +/- 1.0 and 50.1 +/- 5.9 minutes, respectively.
R W, Derlet, T E, Albertson, P, Rice
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Tolerance to d-amphetamine: Behavioral specificity
Life Sciences, 1976Abstract In a Y-maze exploratory task mice tend to enter that compartment which was least recently visited (spontaneous alternation). Low doses of d-amphetamine (1.0 mg/kg) reduce alternation to chance levels, while high doses (10.0 mg/kg) result in animals successively visiting only two compartments of the Y-maze (perseveration).
L, Kokkinidis +3 more
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Sociopharmacology of d-amphetamine in Macaca arctoides
Pharmacology Biochemistry and Behavior, 1980This study was designed to assess the effects of acute d-amphetamine pretreatment on the social behavior of a heterosexual group of adult M. arctoides. The dominance status had been previously determined by use of daily group food competition tests. Prior to some sessions amphetamine was administered to a single group member; whereas on other occasions
A, Bellarosa, J A, Bedford, M C, Wilson
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d-amphetamine binding to brain lipid
Neurochemical Research, 1978The interaction of d-amphetamine with several brain tissue components has been investigated. A brain lipid extract and a number of individual phospholipids were found to bind d-amphetamine when measured by means of a hexane-buffer partition coefficient technique.
M A, Goldberg, T, Todoroff
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Journal of the Neurological Sciences, 1975
Guinea pigs exhibit an increased sensitivity to both d-amphetamine- and apomorphine-induced stereotyped behavior following chronic pretreatment with d-amphetamine. This chronic agonist or "innervation" supersensitivity is believed to be a reflection of an increased sensitivity of dopamine receptor sites within the corpus striatum to dopaminergic ...
H L, Klawans +3 more
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Guinea pigs exhibit an increased sensitivity to both d-amphetamine- and apomorphine-induced stereotyped behavior following chronic pretreatment with d-amphetamine. This chronic agonist or "innervation" supersensitivity is believed to be a reflection of an increased sensitivity of dopamine receptor sites within the corpus striatum to dopaminergic ...
H L, Klawans +3 more
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Drug and Alcohol Dependence, 2004
Flexibility of drug taking is characteristic for "controlled" drug consumption whereas addiction is reflected by inflexibility and persistent high risk to relapse. Male Wistar rats (N = 12) that were given a continuous free choice between water and D-amphetamine solutions for 16 weeks, revealed a moderate and flexible pattern of D-amphetamine intake ...
Gabriel, Galli, Jochen, Wolffgramm
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Flexibility of drug taking is characteristic for "controlled" drug consumption whereas addiction is reflected by inflexibility and persistent high risk to relapse. Male Wistar rats (N = 12) that were given a continuous free choice between water and D-amphetamine solutions for 16 weeks, revealed a moderate and flexible pattern of D-amphetamine intake ...
Gabriel, Galli, Jochen, Wolffgramm
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