Results 161 to 170 of about 42,834 (276)

Bioactivation and Metabolism of Amino Acid MDMA Prodrugs in Zebrafish Embryos, Human Liver S9, Whole Blood, and Microdosed Human Urine

open access: yesDrug Testing and Analysis, Volume 18, Issue 5, Page 669-677, May 2026.
Bioactivation and metabolism of MDMA prodrugs: MDMA‐Trp, MDMA‐Lys, MDMA‐Gly showed unique urine screening targets only for MDMA‐Trp, while biomarkers for MDMA‐Lys and MDMA‐Gly consisted of MDMA and known MDMA metabolites. Conversion of amino acid prodrugs to MDMA in pHLS9, zebrafish embryos, and humans. ABSTRACT 3,4‐Methylenedioxymethamphetamine (MDMA)
Simon K. Wellenberg   +6 more
wiley   +1 more source

Anticipation of monetary reward in amygdala, insula, caudate are predictors of pleasure sensitivity to d-Amphetamine administration. [PDF]

open access: yesDrug Alcohol Depend, 2020
Langenecker SA   +8 more
europepmc   +1 more source

Natural Products as the Modulators of Gut Microbiota: A Pool for the Development of New Treatment Against Obesity?

open access: yesFood Frontiers, Volume 7, Issue 3, May 2026.
Natural compounds regulate gut microbiota by improving microbial balance and increasing probiotics, which boost short‐chain fatty acid production to alleviate insulin resistance and inflammation. Additionally, they stimulate appetite‐suppressing hormones through bile acid signaling, while inhibiting pathogenic bacteria to repair intestinal barrier ...
Hongchao Yuan   +7 more
wiley   +1 more source

ADHD medications and drug withdrawal: A pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) database

open access: yes
Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
Takumi Ebina   +2 more
wiley   +1 more source

Personality Pathology and Functional Outcomes During Pharmacological Treatment of Adult ADHD

open access: yesPersonality and Mental Health, Volume 20, Issue 2, May 2026.
ABSTRACT Adults with ADHD show substantial variability in response to pharmacological treatment, and comorbid personality pathology may help explain why symptom improvement often fails to translate into meaningful functional improvement. This naturalistic longitudinal study examined whether dimensional personality pathology predicts symptomatic and ...
Peter Jacobsson   +6 more
wiley   +1 more source

Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos   +3 more
wiley   +1 more source

Improving drug identification in overdose death surveillance by using clinical natural language processing models

open access: yesJournal of Forensic Sciences, Volume 71, Issue 3, Page 1329-1337, May 2026.
Abstract The rising rate of drug‐related deaths in the United States, largely driven by fentanyl, requires timely and accurate surveillance. However, critical overdose data are often buried in free‐text coroner reports, leading to delays and information loss when coded into ICD (International Classification of Disease)‐10 classifications.
Arthur J. Funnell   +8 more
wiley   +1 more source

Trends in toxicological findings and drug seizures of MDMA in New Zealand from 2010 to 2022

open access: yesJournal of Forensic Sciences, Volume 71, Issue 3, Page 1338-1350, May 2026.
Abstract 3,4‐Methylenedioxymethamphetamine (MDMA) or “ecstasy,” is a commonly used drug worldwide, including in New Zealand, where 4.8% of the population aged 15 years or over reported using it in a 2023/2024 survey. This study provides additional insights on MDMA prevalence data in New Zealand by reporting toxicology data from Coronial and driving ...
Thomas J. Sheehan   +4 more
wiley   +1 more source

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