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PLoS ONE, 2021 IntroductionCoronavirus Disease 2019 is a primarily respiratory illness that can cause thrombotic disorders. Elevation of D-dimer is a potential biomarker for poor prognosis in COVID-19, though optimal cutoff value for D-dimer to predict mortality has ...
Ayusha Poudel +7 more
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The poor prognosis and influencing factors of high D-dimer levels for COVID-19 patients
Scientific Reports, 2021 To explore the value, and influencing factors, of D-dimer on the prognosis of patients with COVID-19. A total of 1,114 patients with confirmed COVID-19 who were admitted to three designated COVID-19 hospitals in Wuhan, China from January 18, 2020, to ...
Xiaokang He +8 more
doaj +2 more sources
American Journal of Hematology, 2019 AbstractD‐dimer is an indirect marker of fibrinolysis and fibrin turnover; this molecule exhibits unique properties as a biological marker of hemostatic abnormalities as well as an indicator of intravascular thrombosis. D‐dimer is a soluble fibrin degradation product that results from the systematic degradation of vascular thrombi through the ...
Eric D. Johnson +2 more
openaire +3 more sources
Respiratory Research, 2020 Background Since December 2019, the outbreak of COVID-19 caused a large number of hospital admissions in China. Many patients with COVID-19 have symptoms of acute respiratory distress syndrome, even are in danger of death.
Wenjing Ye +14 more
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D‐dimer testing in clinical practice in the era of COVID‐19
Research and Practice in Thrombosis and Haemostasis, 2022 D‐dimer is a fragment of crosslinked fibrin resulting from plasmin cleavage of fibrin clots and hence an indirect biomarker of the hemostatic system activation.
Claire Auditeau +5 more
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Thrombosis Journal, 2021 Background Data on the prognostic role of D-dimer in patients with acute coronary syndrome (ACS) are controversial. Our aim was to summarize current evidence on the association between D-dimer levels and short/long-term poor prognosis of ACS patients. We
Flavio Giuseppe Biccirè +5 more
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Haematologica, 2023 D-dimer, a soluble fibrin degradation product that originates from plasmin-induced degradation of cross-linked fibrin, is an important biomarker of coagulation activation and secondary fibrinolysis that is routinely used to rule out venous ...
Massimo Franchini +3 more
semanticscholar +1 more source
D-dimer kit with a High FDP/D-Dimer Ratio is Useful for Diagnosing Thrombotic Diseases
Clinical and Applied Thrombosis/Hemostasis, 2022 Introduction Although D-dimer is a useful biomarker of thrombosis, there are many D-dimer kits, with high and low fibrinogen and fibrin degradation products (FDP)/ D-dimer ratios.
Nozomi Ikeda +10 more
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Performance of age-adjusted D-dimer values for predicting DVT before the knee and hip arthroplasty
Journal of Orthopaedic Surgery and Research, 2021 Purpose To compare the specificity and sensitivity of preoperative D-dimer and age-adjusted D-dimer value for predicting the incidence of the DVT preoperatively in total joint arthroplasty (TJA) patients. Methods We enrolled 406 patients finally above 50
Jian Xiang Wu +4 more
doaj +1 more source
Diagnostic Value of D-Dimer in COVID-19: A Meta-Analysis and Meta-Regression
Clinical and applied thrombosis/hemostasis, 2021 The prognostic role of hypercoagulability in COVID-19 patients is ambiguous. D-dimer, may be regarded as a global marker of hemostasis activation in COVID-19.
H. Zhan +6 more
semanticscholar +1 more source