Results 141 to 150 of about 15,447,907 (346)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Prevalence of pulmonary embolism in patients with COVID-19 pneumonia and high D-dimer values: A prospective study

PLoS ONE, 2020
Introduction Coronavirus disease 2019 (COVID-19) pneumonia is associated to systemic hyper-inflammation and abnormal coagulation profile. D-dimer elevation is particularly frequent, and values higher than 1μg/mL have been associated with disease severity
A. Alonso-Fernández, Nuria Toledo-Pons, B. Cosío, A. Millán, Néstor Calvo, L. Ramón, Sara Hermoso de Mendoza, D. Morell-Garcia, Josep Miquel Bauça-Rossello, Belén Núñez, J. Pons, J. Palmer, L. Martín, M. Peñaranda, J. Pou, J. Sauleda, Ernest Sala-Llinás   +16 more
semanticscholar   +1 more source

Pengaruh Pemberian Heparin Subkutan Sebagai Profilaksis Trombosis Vena Dalam (Tvd) Terhadap Nilai D-dimer Pada Pasien Sakit Kritis Di Icu Rsup Dr. Kariadi [PDF]

, 2013
Latar Belakang : Pasien sakit kritis adalah pasien dengan penyakit atau kondisi yang mengancam keselamatan jiwa pasien tersebut. Pasien dengan kondisi semacam ini memiliki risiko yang tinggiterhadap kejadian komplikasiseperti trombosis vena dalam (TVD ...
Arifin, J. (Johan), Kartadi, D. H. (David)   +1 more
core  

Crotalus atrox venom preconditioning increases plasma fibrinogen and reduces perioperative hemorrhage in a rat model of surgical brain injury. [PDF]

, 2017
Perioperative bleeding is a potentially devastating complication in neurosurgical patients, and plasma fibrinogen concentration has been identified as a potential modifiable risk factor for perioperative bleeding.
Applegate, Richard, Bull, Brian S, Gren, Eric CK, Hay, Karen L, Hayes, William K, Kelln, Wayne, Kim, Cherine H, Lekic, Tim, McBride, Devin W, Raval, Ronak, Sherchan, Prativa, Tang, Jiping, Zhang, John H   +12 more
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

The use of the rapid D-dimer test for the exclusion of acute venous thromboembolism in a regional hospital. [PDF]

, 2003
The performance of rapid D-dimer ELISA assay has been validated as a part of various diagnostic work-ups in tertiary care hospitals for the exclusion of acute thromboembolism in the medical emergency department.
Cornuz, J., Fumeaux, T.
core  

Enhancing Strength and Electrical Conductivity in Al–Zr–Sc Conductor Alloys Through Sn and Sr Microalloying and Two‐Step Aging Treatment

Advanced Engineering Materials, EarlyView.
Trace additions of Sn and Sr combined with a two‐step aging treatment are shown to enhance the microstructure and performance of Al–Zr–Sc conductor alloys. Strength and electrical conductivity increase concurrently through accelerated precipitation of fine Al3(Sc, Zr) precipitates and improved dislocation resistance, offering a cost‐effective pathway ...
Quan Shao, Emad M. Elgallad, Alexandre Maltais, X.‐Grant Chen   +3 more
wiley   +1 more source

Fibrinogen and D-dimer variances and anticoagulation recommendations in Covid-19: current literature review.

Revista da Associação Médica Brasileira, 2020
INTRODUCTION Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly described virus responsible for the outbreak of the coronavirus disease 2019 (Covid-19), named by the World Health Organization (WHO) in February/2020.
M. Hayıroğlu, Tufan Çınar, A. Tekkeşin   +2 more
semanticscholar   +1 more source

Enhancing Optoelectronic Properties in Phthalocyanine‐Based SURMOFs: Synthesis of ABAB Linkers by Avoiding Statistical Condensation with Tailored Building Blocks

Advanced Functional Materials, EarlyView.
A novel phthalocyanine (PC)‐based metal–organic framework (MOFs) is synthesized using ditopic PC linkers obtained through regioselective statistical condensation. The resulting MOF exhibits significant improvements in electronic absorption, thereby enhancing the material's performance in light harvesting and energy conversion.
Lukas S. Langer, Mareen Stahlberger, Xiaojing Liu, Yi Luo, Niklas E. Häußermann, Puja Singhvi, Yidong Liu, Olaf Fuhr, Martin Nieger, Lars Heinke, Thomas Heine, Christof Wöll, Stefan Bräse   +12 more
wiley   +1 more source

Increased tumor necrosis factor alpha and interleukin-6 serum levels and their correlation with laboratory parameters in patients with imported malaria [PDF]

, 2012
In malaria, blood concentrations of proinflammatory cytokines, such as tumor necrosis factor alpha (TNF-α) and interleukin (IL)-6, are increased. In a study which included 34 patients, TNF-α and IL-6 were examined in two phases, immediately after the ...
Dakić Zorica, Dopsaj Violeta, Dunjić Radica, Maksić N., Pavlović Milorad, Poluga Jasmina, Stojaković Sonja, Veljković Milena   +7 more
core   +1 more source