Results 41 to 50 of about 824,647 (268)

Solid-State Pulsed Time-of-Flight 3-D Range Imaging Using CMOS SPAD Focal Plane Array Receiver and Block-Based Illumination Techniques

IEEE Photonics Journal, 2022
Full realization of a solid-state 3-D range imager based on the pulsed time-of-flight method is presented. The system uses block-based segmented illumination in the transmitter realized with a 16-element common anode laser diode bar.
Juha Kostamovaara, Sahba Jahromi, Lauri Hallman, Guoyong Duan, Jussi-Pekka Jansson, Pekka Keranen   +5 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

The Case of Dr. John D. Frame′s First Memory: Historical Truth and Psychological Distortion

Consciousness and Cognition, 1995
L'A. etudie le probleme des distorsions et de la fabrication des souvenirs de l'enfance, dans le cadre de la therapie de la memoire et de ses implications psychologiques et legales. L'A. (J. D. Frame) relate le contenu de sa premiere memoire et confronte son jugement a celui du co-auteur de cet article (M. H. Erdelyi)
M H, Erdelyi, J D, Frame
openaire   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

High-Frame-Rate 3-D Vector Flow Imaging in the Frequency Domain

Applied Sciences, 2020
Ultrasound vector Doppler techniques for three-dimensional (3-D) blood velocity measurements are currently limited by low temporal resolution and high computational cost.
Stefano Rossi, Alessandro Ramalli, Fabian Fool, Piero Tortoli   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Construction of new curves on nth degree polynomial-type curves using the Flc frame

Demonstratio Mathematica
In this study, first, the pedal curves were defined as the geometric locus of perpendicular projections onto the Frenet-like frame (Flc) vectors T, D 2, and D 1 of a given polynomial curve.
Şenyurt Süleyman, Damar Esra
doaj   +1 more source

Interactive Microcomputer Graphics Environment for Integrated Analysis and Design of 2-D Framed Structures

Computer-Aided Civil and Infrastructure Engineering, 1987
An interactive graphics microcomputer program for the analysis and design of 2-D framed structures is described in this paper. The system is designed to utilize the full power of microcomputer graphics technology and recent advances in computer science.
SAID I. HILMY, KENNETH E. MORROW
openaire   +1 more source