Results 101 to 110 of about 14,270,526 (371)
D-galactose induces senescence of glioblastoma cells through YAP-CDK6 pathway
Aging, 2020 Treatment of glioblastoma using radiotherapy and chemotherapy has various outcomes, key among them being cellular senescence. However, the molecular mechanisms of this process remain unclear.
Xingxing Xu +17 more
semanticscholar +1 more source
Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics
Advanced Science, EarlyView.The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu +4 more
wiley +1 more source
The D‐mannose/L‐galactose pathway plays a predominant role in ascorbate biosynthesis in the liverwort Marchantia polymorpha but is not regulated by light and oxidative stress [PDF]
, 2023 Tetsuya Ishida +3 more
openalex +1 more source
Nutrition Research and Practice, 2020 BACKGROUND/OBJECTIVES Brain aging is a major risk factor for severe neurodegenerative diseases. Conversely, L-histidine and L-carnosine are known to exhibit neuroprotective effects.
Yerin Kim, Yuri Kim
semanticscholar +1 more source
The application of nitrido manganese reagents to the synthesis of protected N-methyl D-fucosamine [PDF]
, 1998 A synthesis of protected D-fucosamine and N-methyl fucosamine from D-galactose is described. The synthesis is carried out in ten steps and includes the amination reaction of D-fucal with an easily prepared Mn≡N ...
Carreira, Erick M. +3 more
core
Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion
Advanced Science, EarlyView.FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao +8 more
wiley +1 more source
Angewandte Chemie, EarlyView.A streamlined platform for glycosite‐specific antibody conjugation is enabled by LacNAc‐derived cyclic acetal donors, which can be prepared in only two steps and used directly in single‐enzyme Endo S2‐mediated transglycosylation. The platform supports the broad construction of homogeneous gsADCs and gsDACs, with donor 7 producing glycoengineered ...
Deqin Cai +13 more
wiley +2 more sources
Poultry Science, 2020 Our patented protease A–digested crude chalaza hydrolysates (CCH) show antioxidant abilities in vitro. The prophylactic effects of CCH on cognitive dysfunction and brain oxidative damages were investigated via a D-galactose (DG)–injected mouse model in ...
Chia-Jung Chan +6 more
doaj +1 more source
Protective effect of walnut on d‐galactose‐induced aging mouse model
Food Science & Nutrition, 2019 Objective (s) Accumulating evidence has suggested that oxidative stress and apoptosis are involved in the aging process. d‐galactose (gal) has been reported to cause symptoms of aging in mice, accompanied by liver and brain injuries. Our present work was
Ji Liu +5 more
semanticscholar +1 more source
The Rapid and Sensitive Quantitative Determination of Galactose by Combined Enzymatic and Colorimetric Method: Application in Neonatal Screening [PDF]
, 2016 The quantitative measurement of galactose in blood is essential for the early diagnosis, treatment, and dietary monitoring of galactosemia patients. In this communication, we aimed to develop a rapid, sensitive, and cost-effective combined method for ...
Ansari, J. +4 more
core +1 more source