Results 331 to 340 of about 14,270,526 (371)
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D-Galactose as a Vector for Prodrug Design
Current Topics in Medicinal Chemistry, 2011D-galactose is a simple and natural compound that has mainly been exploited in prodrug strategies. Galactosyl prodrugs can be considered a good approach to reach different goals in clinical drug application, especially when traditional drugs are likely to fail therapeutically owing to reasons such as the lack of site specificity, toxicity, and chemical
MELISI, DANIELA +4 more
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Biochemical and Biophysical Research Communications, 1973
Abstract The pathway by which D-galactose 6-phosphate is degraded in Staphylococcus aureus has been elucidated. Galactose 6-phosphate is isomerized to tagatose 6-phosphate, which is phosphorylated with adenosine 5′-triphosphate, and the resulting tagatose 1,6-diphosphate is cleaved to dihydroxyacetone phosphate and glyceraldehyde 3-phosphate.
Donald L. Bissett, Richard L. Anderson
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Abstract The pathway by which D-galactose 6-phosphate is degraded in Staphylococcus aureus has been elucidated. Galactose 6-phosphate is isomerized to tagatose 6-phosphate, which is phosphorylated with adenosine 5′-triphosphate, and the resulting tagatose 1,6-diphosphate is cleaved to dihydroxyacetone phosphate and glyceraldehyde 3-phosphate.
Donald L. Bissett, Richard L. Anderson
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The American Journal of Chinese Medicine, 2020
Oxidative stress is considered as a major factor in aging and exacerbates aging process through a variety of molecular mechanisms. D-galactose, a normal reducing sugar with high dose can cause the accumulation of reactive oxygen species (ROS) or ...
Wei Li +9 more
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Oxidative stress is considered as a major factor in aging and exacerbates aging process through a variety of molecular mechanisms. D-galactose, a normal reducing sugar with high dose can cause the accumulation of reactive oxygen species (ROS) or ...
Wei Li +9 more
semanticscholar +1 more source
Journal of the Chemical Society C: Organic, 1966
The 6-methacryloyl and 6-acryloyl esters of 1,2:3,4-di-O-isopropylidene-α-D-galactopyranose have been synthesised and polymerised to polymers of high molecular weight. The isopropylidene blocking groups have been removed by treatment with formic acid–water at 20°, to give poly-(6-O-methacryloyl-D-galactose) and poly-(6-O-acryloyl-D-galactose); which ...
T P, Bird +4 more
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The 6-methacryloyl and 6-acryloyl esters of 1,2:3,4-di-O-isopropylidene-α-D-galactopyranose have been synthesised and polymerised to polymers of high molecular weight. The isopropylidene blocking groups have been removed by treatment with formic acid–water at 20°, to give poly-(6-O-methacryloyl-D-galactose) and poly-(6-O-acryloyl-D-galactose); which ...
T P, Bird +4 more
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Synthesis of 5-thio-D-galactose
Carbohydrate Research, 1979Abstract A synthesis of 5-thio- D -galactose, in the form of its crystalline, anomeric methyl glycopyranosides, is described. Compounds prepared as intermediates included ethyl 2,3-di-O-(tert-butyldimethylsilyl)-5,6-O-carbonyl-β- D -galactofuranoside, the corresponding 5,6-dideoxy-5,6-epithio derivative, and ethyl 2,3,6-tri-O-acetyl-5-S-acetyl-5-thio-
Jeong E. Nam Shin, Arthur S. Perlin
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The Methyl Ethers of D-Galactose
1951Publisher Summary This chapter discusses methyl ethers of D -galactose. The 2,3,4,6-tetramethyl- D -galactopyranos is obtained by the full methylation of the methyl α- or β- D -galactopyranosides, followed by acid hydrolysis of the products.
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Substrate specificity of D-galactose oxidase
Carbohydrate Research, 1968Abstract The rate of oxidation of methyl ethers of D -galactose and 2-amino-2-deoxy- D -galactose, and of oligosaccharides and polysaccharides containing D -galactosyl residues having a free hydroxyl group at C-6, has been followed by various procedures that depend either upon the hydrogen peroxide or the aldehyde groups produced, or upon the ...
Robert A. Schlegel +2 more
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The Methyl Ethers of D-Galactose
1955Publisher Summary This chapter presents a set of tables of the physical characteristics of the methyl ethers of D-galactose and their derivatives, replaces those of D. J. Bell, Advances in Carbohydrate Chem.
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Prevention of experimental liver metastases by D-galactose
Experientia, 1987The metastasis of malignant tumors from a primary site to near and distant secondary sites is probably the most important event in the pathogenesis of cancer and it accounts for most cancer deaths. Whereas advances in the treatment of primary cancer have led to increased patient survival, metastatic cancers are still the most difficult group of ...
G, Uhlenbruck +4 more
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Anti-Apoptotic Effects of Diosgenin in D-Galactose-Induced Aging Brain.
The American Journal of Chinese Medicine, 2020The purpose of this study was to evaluate the effects of diosgenin on the D-galactose-induced cerebral cortical widely dispersed apoptosis. Male 12-week-old Wistar rats were divided into four groups: Control (1mg/kg/day of saline, i.p.), DD0 (150mg/kg ...
Shiu-Min Cheng +8 more
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