Biogerontology (Dordrecht), 2020 The cochlear basilar membrane (CBM) contains inner hair cells and outer hair cells that convert sound waves into electrical signals and transmit them to the central auditory system.
Bin Guo +6 more
semanticscholar +1 more source
Inactivation of metabolic genes causes short- and long-range dys-regulation in Escherichia coli metabolic network. [PDF]
PLoS ONE, 2013 The metabolic network in E. coli can be severely affected by the inactivation of metabolic genes that are required to catabolize a nutrient (D-galactose).
Dinesh Kumar Barupal +3 more
doaj +1 more source
International Journal of Molecular Sciences, 2020 Aging is an oxidative stress-associated process that progresses with age. Our aim is to delay or attenuate these oxidative alterations and to keep individuals healthy as they age using natural compounds supplementation.
A. El‑Far +6 more
semanticscholar +1 more source
Prevention of Protein Glycation by Natural Compounds [PDF]
, 2015 Non-enzymatic protein glycosylation (glycation) contributes to many diseases and aging of organisms. It can be expected that inhibition of glycation may prolong the lifespan.
Bartosz, Grzegorz +1 more
core +2 more sources
Galactose and its Metabolites Deteriorate Metaphase II Mouse Oocyte Quality and Subsequent Embryo Development by Disrupting the Spindle Structure [PDF]
, 2017 Premature ovarian insufficiency (POI) is a frequent long-term complication of classic galactosemia. The majority of women with this disorder develop POI, however rare spontaneous pregnancies have been reported. Here, we evaluate the effect of D-galactose
Abu-Soud, Husam M +7 more
core +2 more sources
Simple method for Shiga toxin 2e purification by affinity chromatography via binding to the divinyl sulfone group. [PDF]
PLoS ONE, 2013 Here we describe a simple affinity purification method for Shiga toxin 2e (Stx2e), a major causative factor of edema disease in swine. Escherichia coli strain MV1184 transformed with the expression plasmid pBSK-Stx2e produced Stx2e when cultivated in ...
Hideyuki Arimitsu +4 more
doaj +1 more source
Laboratory Animal Research, 2017 In the present study, we examined the effects of Dendropanax morbifera Léveille leaf extract (DML) on dgalactose-induced morphological changes in microglia and cytokines, including pro-inflammatory cytokines (interleukin [IL]-1β, IL-6, and tumor necrosis
Kwon Young Lee +9 more
doaj +1 more source
Halorubrum chaoviator sp. nov., a haloarchaeon isolated from sea salt in Baja California, Mexico, Western Australia and Naxos, Greece [PDF]
, 2009 hree halophilic isolates, strains Halo-G*T, AUS-1 and Naxos II, were compared. Halo-G* was isolated from an evaporitic salt crystal from Baja California, Mexico, whereas AUS-1 and Naxos II were isolated from salt pools in Western Australia and the Greek ...
Legat, Andrea +5 more
core +1 more source
Metformin alleviates neurocognitive impairment in aging via activation of AMPK/BDNF/PI3K pathway
Scientific Reports, 2022 Slowing down age-related neurocognitive impairment has been a challenge. We evaluated the therapeutic effects of metformin in d-galactose-induced aging. Additionally, we studied the potential molecular mechanisms that could be responsible for metformin's
Omnia Ameen +2 more
doaj +1 more source
Assessment of sub-chronic toxicity and anti-aging effects of a solid self-microemulsifying drug delivery system of <i>Kaempferia parviflora</i> extract in a D-galactose-induced rat model. [PDF]
Pharm BiolSomintara S +8 more
europepmc +2 more sources