Results 91 to 100 of about 15,326,315 (274)
D-Glucosamine in a chimeric prolinamide organocatalyst for direct asymmetric aldol addition [PDF]
, 2012 O-TBDPS d-glucosamine coupled with l-proline is reported to act as an efficient organocatalyst in the accomplishment of direct aldol reactions. Excellent results, in terms of chemical yields, as well as diastereomeric and enantiomeric ratios, are ...
Bektas S. +4 more
core +1 more source
Exploring the Potential and Advancements of Circular RNA Therapeutics
Exploration, EarlyView.Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang +6 more
wiley +1 more source
The Pleiotropic Effects of Beneficial Mutations of Adapted Escherichia coli Populations [PDF]
, 2014 Mutations that improve fitness in one environment can often be beneficial, deleterious, or neutral in alternative environments. When a single mutation effects fitness in multiple environments, it is said to be a pleiotropic, which can have important ...
Van Dam, Brian Scott
core +1 more source
Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley +1 more source
Ibrain, EarlyView.Polysaccharide‐based nanoparticles offer versatile platforms for drug delivery and immune modulation in neurodegenerative diseases. This review highlights their potential in treating Alzheimer's, Parkinson's, and multiple sclerosis, focusing on targeted delivery and neuroinflammation.
Leto‐Aikaterini Tziveleka +5 more
wiley +1 more source
Evidence base of pharmaconutraceuticals with chondroprotective action
Лечащий ВрачBackground. Osteoarthritis is one of the most common chronic diseases of the musculoskeletal system worldwide, being a common cause of chronic pain syndrome and disability.
O. A. Shavlovskaya +2 more
doaj +1 more source
Synthesis and bioactivity of a conjugate composed of green tea catechins and hyaluronic acid [PDF]
, 2015 (-)-Epigallocatechin-3-gallate (EGCG) is a green tea polyphenol that has several biological activities, including anti-cancer activity and anti-inflammation.
Chung, Joo Eun +7 more
core +1 more source
Synthetic biology for medical biomaterials
Interdisciplinary Medicine, EarlyView.Synthetic biology platform has been utilized to produce a variety of medical biomaterials (MBMs), such as polylactic acid (PLA), polyhydroxyalkanoates (PHAs), hyaluronic acid (HA), collagen (COL), poly(β‐malic acid) (PMLA), poly‐γ‐glutamic acid (γ‐PGA), alginate (ALG), chitosan (CS), bacterial cellulose (BC), and antimicrobial peptides (AMPs).
Tao Xu +4 more
wiley +1 more source
Chitin and lignin. Natural ingredients from waste materials to make innovative and healthy products for humans and plant [PDF]
, 2017 In a globalized world, plants are continually cut to obtain free land for intensive farming without remembering their important function in the planet ecosystem.
Morganti, Pierfrancesco, Stoller, Marco
core +1 more source
Interdisciplinary Medicine, EarlyView.Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang +12 more
wiley +1 more source