Results 101 to 110 of about 66,840 (319)
: l-Glutamine, quercetin, slippery elm bark, marshmallow root, N-acetyl-d-glucosamine, licorice root, maitake mushrooms, and zinc orotate have been reported to help treat leaky gut.
Ricardo S. Aleman+4 more
doaj
Synthesis of Rare‐Bacterial Sugar Analogs: Thomosamine and Fluorinated Thomosamine
We present the synthesis of protected thomosamine (4‐amino‐4,6‐dideoxy‐d‐galactopyranose), 3‐deoxy‐3‐fluoro‐thomosamine, and 2,3‐dideoxy‐2,3‐difluoro‐thomosamine from levoglucosan (1,6‐anhydro‐β‐d‐glucopyranose). Bacterial carbohydrates that include unusual deoxy amino sugars represent interesting targets in drug discovery.
Sam Bahadori+2 more
wiley +1 more source
Contactless Conductivity Detection for Capillary Electrophoresis—Developments From 2020 to 2024
ABSTRACT The review covering the development of capillary electrophoresis with capacitively coupled contactless conductivity detection from 2020 to 2024 is the latest in a series going back to 2004. The article considers applications employing conventional capillaries and planar lab‐on‐chip devices as well as fundamental and technical developments of ...
Peter C. Hauser, Pavel Kubáň
wiley +1 more source
The use of chitin binding proteins for glycoprotein analysis [PDF]
The focus of the pharmaceutical industry has dramatically shifted in the past number of years. Traditional drugs were synthesised using chemical reactions have been replaced by recombinant glycoprotein molecules.
Larragy, Ruth+2 more
core
Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate [PDF]
Hen egg-white lysozyme (HEWL) was the first enzyme to have its three-dimensional structure determined by X-ray diffraction techniques(1). A catalytic mechanism, featuring a long-lived oxo-carbenium-ion intermediate, was proposed on the basis of model ...
A Federov+28 more
core +1 more source
Exploring the Potential and Advancements of Circular RNA Therapeutics
Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang+6 more
wiley +1 more source
Two water‐soluble polysaccharides were isolated and purified from Tricholoma flavovirens (TF‐P) and Trametes versicolor (TV‐P), respectively. The structures of the two polysaccharides were identified by combining GPC, FT‐IR, HPLC, GC–MS, and NMR, and the structure–activity relationship has also been studied using immune cells and tumor cells. TV‐P with
Zheng‐Ao Sun+5 more
wiley +1 more source
GDP-mannose pyrophosphorylase gene (ManC) of Escherichia coli (E. coli) O157 was cloned and expressed as a highly soluble protein in E. coli BL21 (DE3). The enzyme was subsequently purified using hydrophobic and ion exchange chromatographies. ManC showed
Hwang, Bum-Yeol+6 more
core
The synthesis of -5-(D-arabino-1,2,3,4-tetrahydroxybutyl)tetrazole and -2-(D-arabino-1,2,3,4-tetra-acetoxybutyl)-5-methyl-1,3,4-oxadiazole from D-arabinose is described.
Renato Márcio Ribeiro Viana+2 more
doaj +1 more source
Abstract Metabolic syndrome (MetS) is a complex noncommunicable condition characterized by central obesity, insulin resistance, hyperlipidemia, hypertension, and hyperglycemia. Epidemiological evidence shows that MetS affects a third of the global population; however, due to its complex pathogenesis and limited drug therapy options, the increasing ...
Josiah Owuor Oyalo+3 more
wiley +1 more source