Results 161 to 170 of about 15,268,560 (303)

Status quo and future developments in the diagnosis and treatment of hereditary angioedema

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Hereditary angioedema (HAE) is a rare hereditary disease characterized by edema, which can be life‐threatening in case of swelling in the larynx. The most common form of HAE is caused by a mutation of the SERPING1 gene and is characterized by a deficiency (type I) or loss of function (type II) of the C1 inhibitor (C1‐INH), leading to excessive ...
Andreas Recke
wiley   +1 more source

Acute severe lameness associated with proliferative bone on the dorsal middle phalanx (19 cases)

open access: yesEquine Veterinary Education, EarlyView.
Summary Background Injury resulting in proliferative new bone formation on the dorsal aspect of the middle phalanx (P2) has been recognised by equine veterinarians and is generally referred to as capsulitis. However, no retrospective case series has been published on the condition. Objectives To describe the clinical features, treatment, and outcome of
J. G. Fowlie   +3 more
wiley   +1 more source

Chromatin folding by the Polycomb group proteins and its elusive role in epigenetic repression

open access: yesThe FEBS Journal, EarlyView.
Genes repressed by the Polycomb system display greater chromatin folding compared to ‘regular’ inactive genes. The associated chromatin compaction, driven by PRC1‐H3K27me3 interactions, is modest and dynamic. This questions traditional models where Polycomb proteins repress transcription by sheltering genes from transcriptional activators.
Ludvig Lizana, Yuri B. Schwartz
wiley   +1 more source

Synthesis of 6-O-Aminoacyl-N-acetyl-D-glucosamines

open access: bronze, 1964
吉村 寿次   +3 more
openalex   +2 more sources

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

open access: yesThe FEBS Journal, EarlyView.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk   +8 more
wiley   +1 more source

Structural characterisation of nucleotide sugar short‐chain dehydrogenases/reductases from the thermophilic pseudomurein‐containing methanogen Methanothermobacter thermautotrophicus ΔH

open access: yesThe FEBS Journal, EarlyView.
Nucleotide sugar short‐chain dehydrogenases/reductases (NS‐SDRs) are involved in pseudomurein and capsular polysaccharide formation in methanogenic Archaea. Methanothermobacter thermautotrophicus possesses several NS‐SDRs labelled Mth375, Mth380, Mth373, Mth631 and Mth1789.
Vincenzo Carbone   +4 more
wiley   +1 more source

Deciphering the interaction between N-palmitoyl-D-glucosamine and the endocannabinoidome. [PDF]

open access: yesSci Rep
Schiano Moriello A   +7 more
europepmc   +1 more source

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