Review of experimental equine synovitis models for inducing lameness
Equine Veterinary Education, EarlyView.Summary Lameness in horses, particularly in relation to osteoarthritis (OA), is complex and variable, highlighting the importance of experimental models in advancing our understanding of pain and lameness. Synovitis plays a critical role in the development of OA, and reversible models of synovitis offer valuable insights into physiology and potential ...
A. Dockery, B. Beasley, V. J. Moorman
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Requirement of a properly acylated beta(1-6)-D-glucosamine disaccharide bisphosphate structure for efficient manifestation of full endotoxic and associated bioactivities of lipid A [PDF]
, 1987 Ichiro Takahashi +9 more
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Synthesis of multiply fluorinated N-acetyl-D-glucosamine and D-galactosamine analogs via the corresponding deoxyfluorinated glucosazide and galactosazide phenyl thioglycosides. [PDF]
Beilstein J Org Chem, 2021 Hamala V +5 more
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The FEBS Journal, EarlyView.Interactions between bacteria and the extracellular matrix are a prerequisite for colonisation and infection. Phylogenetically diverse M proteins of group A Streptococcus (GAS) can selectively bind sulfated glycosaminoglycans with high affinity. M protein‐mediated recruitment of chondroitin sulfate and dermatan sulfate was shown to increase GAS ...
Tahnee B.‐D. McEwan +8 more
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Flavobacterium heparinum sulphamidase for D-glucosamine sulphamate. Purification and characterisation [PDF]
, 1987 John S. Bruce +3 more
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N-palmitoyl-D-glucosamine, a Natural Monosaccharide-Based Glycolipid, Inhibits TLR4 and Prevents LPS-Induced Inflammation and Neuropathic Pain in Mice. [PDF]
Int J Mol Sci, 2021 Iannotta M +19 more
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Chromatin folding by the Polycomb group proteins and its elusive role in epigenetic repression
The FEBS Journal, EarlyView.Genes repressed by the Polycomb system display greater chromatin folding compared to ‘regular’ inactive genes. The associated chromatin compaction, driven by PRC1‐H3K27me3 interactions, is modest and dynamic. This questions traditional models where Polycomb proteins repress transcription by sheltering genes from transcriptional activators.
Ludvig Lizana, Yuri B. Schwartz
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Nutrition Bulletin, EarlyView.ABSTRACT Expanding and aging populations, sustainability drivers and changing attitudes to the way we eat mean that there has been growing interest in non‐animal derived protein food sources. Given this shift, there has been an uprise in consumer demand and commercial innovation of meat analogues and alternative protein food sources. The question, with
Emma J. Derbyshire +9 more
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Spatial metabolic and phenotypic characterization of the germ‐free mouse model
Annals of the New York Academy of Sciences, EarlyView.The germ‐free mouse model is a useful tool to understand the influence of the gut microbiota on host physiology. Using spatial metabolomics approaches we mapped the systemic location of small molecules in germ free and colonized mice, focusing on the intestine, spleen, lung, liver, and kidney.
Lauren Adams +8 more
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