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An efficient enzymatic production of N-acetyl-d-glucosamine from crude chitin powders

Green Chemistry, 2016
In this study, we present an efficient affinity adsorption–enzymatic reaction integrated approach to produce N-acetyl-D-glucosamine (GlcNAc) from crude chitin powders (CP). Chitinase was first purified from the crude enzyme mixture by affinity adsorption
Alei Zhang   +4 more
semanticscholar   +1 more source

Production of N-Acetyl-d-glucosamine from Mycelial Waste by a Combination of Bacterial Chitinases and an Insect N-Acetyl-d-glucosaminidase.

Journal of Agricultural and Food Chemistry, 2016
N-Acetyl-d-glucosamine (GlcNAc) has great potential to be used as a food additive and medicine. The enzymatic degradation of chitin-containing biomass for producing GlcNAc is an eco-friendly approach but suffers from a high cost.
Weixing Zhu   +3 more
semanticscholar   +1 more source

Conversion of chitin derived N-acetyl-D-glucosamine (NAG) into polyols over transition metal catalysts and hydrogen in water

, 2015
N-Acetyl-D-glucosamine (NAG), the monomer of the world's second most abundant biopolymer chitin, has been for the first time converted to its corresponding amide/amino substituted sugar alcohols, smaller C2–4 polyols and N-acetylmonoethanolamine (NMEA ...
Felix D. Bobbink   +6 more
semanticscholar   +1 more source

Synthesis of chitin and chitosan stereoisomers by thermostable α-glucan phosphorylase-catalyzed enzymatic polymerization of α-D-glucosamine 1-phosphate.

Organic and biomolecular chemistry, 2015
The relationship between two aminopolysaccharide stereoisomers, namely α-(1→4)- and β-(1→4)-linked (N-acetyl)-D-glucosamine polymers, is of significant interest within the field of polysaccharide science, as they correspond to amino analogs of the ...
J. Kadokawa   +3 more
semanticscholar   +1 more source

Scalable Synthesis of Anomerically Pure Orthogonal-Protected GlcN3 and GalN3 from d-Glucosamine.

Organic Letters, 2016
An improved and scalable synthesis of orthogonally protected d-glucosamine and d-galactosamine building blocks from inexpensive d-glucosamine has been developed.
Emil Glibstrup, C. Pedersen
semanticscholar   +1 more source

A novel D-glucosamine-derived pyridyl-triazole@palladium catalyst for solvent-free Mizoroki–Heck reactions and its application in the synthesis of Axitinib

, 2015
A green method for the synthesis of a D-glucosamine-derived triazole@palladium catalyst is described. The synthesized catalyst containing a 2-pyridyl-1,2,3-triazole ligand was prepared via a click route in high yields and was explored in Heck cross ...
Chao Shen   +4 more
semanticscholar   +1 more source

Conversion of chitin and N-acetyl-D-glucosamine into a N-containing furan derivative in ionic liquids

, 2015
Direct conversion of chitin to 3-acetamido-5-acetylfuran (3A5AF) in a range of ionic liquids (ILs) has been systematically investigated. 10 ILs with different cations and anions were tested as the solvent and 25 additives were screened.
Xi Chen, Yi Liu, F. Kerton, N. Yan
semanticscholar   +1 more source

Enhanced antitumor efficacy by d-glucosamine-functionalized and paclitaxel-loaded poly(ethylene glycol)-co-poly(trimethylene carbonate) polymer nanoparticles.

Journal of Pharmacy and Science, 2014
The poor selectivity of chemotherapeutics for cancer treatment may lead to dose-limiting side effects that compromise clinical outcomes. To solve the problem, surface-functionalized polymer nanoparticles are regarded as promising tumor-targeting delivery
Xinyi Jiang   +6 more
semanticscholar   +1 more source

An efficient D-glucosamine-based copper catalyst for C–X couplings and its application in the synthesis of nilotinib intermediate

, 2015
D-Glucosamine has been studied for C–N and C–S bond formations via cross-coupling reactions of nitrogen and sulfur nucleophiles with both aryl iodides and bromides.
M. Wen   +4 more
semanticscholar   +1 more source

Efficient one-pot synthesis of deoxyfructosazine and fructosazine from D-glucosamine hydrochloride using a basic ionic liquid as a dual solvent-catalyst

, 2014
An efficient one-pot dehydration process for convert D-glucosamine hydrochloride (GlcNH2) into 2-(D-arabino-1′,2′,3′,4′-tetrahydroxybutyl)-5-(D-erythro-2′′,3′′,4′′-trihydroxybutyl)pyrazine (deoxyfructosazine, DOF) and 2,5-bis-(D-arabino-1,2,3,4 ...
Lingyu Jia   +4 more
semanticscholar   +1 more source

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