Results 81 to 90 of about 15,268,560 (303)
PLoS ONE, 2014 Chitosan is a linear heteropolymer consisting of β 1,4-linked N-acetyl-D-glucosamine (GlcNAc) and D-glucosamine (GlcN). We have compared the antifungal activity of chitosan with DPn (average degree of polymerization) 206 and FA (fraction of acetylation ...
Md Hafizur Rahman +6 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective To identify and summarize existing telerehabilitation interventions for people living with rheumatic and musculoskeletal diseases (RMDs), including the rehabilitation components, the technology used, the type of health care professional (HCP) interaction, and how the effectiveness is evaluated.
Thomas A. Ingram +5 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.Optimizing media for potential probiotic Streptococcus thermophilus biomass and exopolysaccharide production was achieved using design of experiments. This was followed by process development in bioreactors, employing fed‐batch strategies, to increase the production of exopolysaccharide, to test it, after membranes purification, on cells proving the ...
Alberto Alfano +5 more
wiley +1 more source
Photo‐Triggered Hyaluronic Acid Hydrogel for 3D Culture and Cell Recovery
ChemBioChem, EarlyView.GA: Cross‐linking of hyaluronic acid modified by a strained alkyne with a photosensitive crosslinker terminating in azides gives hydrogels with tuneable mechanical properties. By tuning the wavelength of employed light, the hydrogel can either be fully degraded allowing harvesting of cultured cells or softened resulting in notable changes in cell ...
Francesco Palmieri +8 more
wiley +1 more source
Functional Analysis of Histidine‐Dependent Self‐Cleaving RNAs Obtained by In Vitro Selection
ChemBioChem, EarlyView.Ribozymes can be nucleic acid medicines given their catalytic activity. We attempted to obtain functional RNAs that mimic ribonuclease A catalytic mechanisms. Functional RNAs with high histidine specificity were obtained, suggesting that histidine acts in active structure formation.
Nae Sakimoto +8 more
wiley +1 more source
Glycosaminoglycans as Polyelectrolytes: Charge, Interactions, and Applications
ChemBioChem, EarlyView.Glycosaminoglycans (GAGs) are linear, anionic biopolymers with their functions tightly linked to their charge. This review approaches GAGs from a polyelectrolyte perspective, shedding light on how the distribution of sulfate groups and, thus, negative charges, governs their interactions with other biomolecules.
Gergo Peter Szekeres +7 more
wiley +1 more source
Química Nova, 2008 The synthesis of -5-(D-arabino-1,2,3,4-tetrahydroxybutyl)tetrazole and -2-(D-arabino-1,2,3,4-tetra-acetoxybutyl)-5-methyl-1,3,4-oxadiazole from D-arabinose is described.
Renato Márcio Ribeiro Viana +2 more
doaj +1 more source
ChemBioChem, EarlyView.Metal‐dithiocarbamato glycoconjugates based on gold(III), gold(I)‐phosphino, and gold(I)‐carbene scaffolds are here investigated as potential anticancer agents. Contrary to expectations, they induce cell death by acting at the extracellular level rather than targeting overexpressed glucose transporters.
Andrea Pettenuzzo +4 more
wiley +1 more source
ChemistryEurope, EarlyView.A borrowing hydrogen strategy using an NHC‐Ir(III) catalyst enables selective N‐functionalization of unprotected amino sugars using alcohols as alkylating agents. The use of unprotected substrates avoids extra steps of protection/deprotection, minimizing waste generation.
Aitor Bermejo‐López +7 more
wiley +1 more source
Finding Drug Candidate Hits With A Hundred Samples: Ultralow Data Screening With Active Learning
ChemistryEurope, EarlyView.Ultra‐low‐data hit discovery becomes practical: starting from randomly selected binders, an active‐learning loop selects only 110 molecules from a 100 k library and have a 100% probability of finding 5 or more top‐1% compounds. Noise tests and alternate libraries confirm robustness, enabling single‐researcher campaigns on smaller budgets.
Jacob M. Nielsen +6 more
wiley +1 more source