Production of low-tannin Hibiscus sabdariffa tea through D-optimal design optimization of the preparation conditions and the catalytic action of new tannase. [PDF]
Highlights • Optimization of preparation conditions of Hibiscus tea was performed.• D-optimal design was applied to obtain anthocyanin-rich and tannin-low Hibiscus tea.• Boiling 2-g calyces/100-ml water for 5 min is the proposed conditions.• Effect of ...
Sayed Mostafa H.
europepmc +2 more sources
Hyaluronic acid-enriched bilosomes: an approach to enhance ocular delivery of agomelatine via D-optimal design: formulation, in vitro characterization, and in vivo pharmacodynamic evaluation in rabbits. [PDF]
Agomelatine (AGO) is a dual-functional drug. It uses as an antidepressant when orally administrated and antiglaucomic when topically applied to the eye.
Nemr AA, El-Mahrouk GM, Badie HA.
europepmc +2 more sources
Preparation, Optimization, and Screening of the Effect of Processing Variables on Agar Nanospheres Loaded with Bupropion HCl by a D-Optimal Design. [PDF]
Bupropion is an atypical antidepressant drug. Fluctuating in its serum levels following oral administration of immediate release dosage forms leads to occasional seizure.
Varshosaz J +3 more
europepmc +2 more sources
Microemulsion-based gel of terbinafine for the treatment of onychomycosis: optimization of formulation using D-optimal design. [PDF]
Barot BS +4 more
europepmc +2 more sources
Efficient D-Optimal Design of Experiments for Infinite-Dimensional Bayesian Linear Inverse Problems [PDF]
We develop a computational framework for D-optimal experimental design for PDE-based Bayesian linear inverse problems with infinite-dimensional parameters.
A. Alexanderian, A. Saibaba
semanticscholar +1 more source
Sparse polynomial chaos expansions via compressed sensing and D-optimal design [PDF]
In the field of uncertainty quantification, sparse polynomial chaos (PC) expansions are commonly used by researchers for a variety of purposes, such as surrogate modeling. Ideas from compressed sensing may be employed to exploit this sparsity in order to
Paul Diaz, A. Doostan, Jerrad Hampton
semanticscholar +1 more source
A-optimal versus D-optimal design of screening experiments
The purpose of this article is to persuade experimenters to choose A-optimal designs rather than D-optimal designs for screening experiments. The primary reason for this advice is that the A-optimality criterion is more consistent with the screening ...
B. Jones, Katherine Allen-Moyer, P. Goos
semanticscholar +1 more source
Optimization of the Ring Opening of Epoxidized Palm Oil using D-Optimal Design
In the presence of a catalyst, p-toluenesulfonic acid (PTSA), the ring of epoxidized palm oil (EPO) was opened using oleic acid (OA). The optimization effects of different process variables including the mol ratio of EPO/OA, reaction temperature, PTSA ...
N. M. Nor, N. Salih, J. Salimon
semanticscholar +1 more source
D-Optimal Design for Network A/B Testing [PDF]
A/B testing refers to the statistical procedure of experimental design and analysis to compare two treatments, A and B, applied to different testing subjects.
V. Pokhilko +3 more
semanticscholar +1 more source
Comparison of Box–Behnken, Central Composite, and D-Optimal Designs for Optimization of Phthalocyanine Dye Removal Using Magnetic Nanoparticles Iron Oxide Modified by Polyaspartic Acid [PDF]
In this study, the performance of the Box–Behnken, central composite and D-optimal designs (BBD, CCD or DOD, respectively) were compared for the use in modeling and optimizing the new study of the removal of phthalocyanine dye using magnetic ...
Javad Zolgharnein +2 more
doaj +1 more source

