Results 51 to 60 of about 3,379,244 (276)
D-optimal population designs in linear mixed effects models for multiple longitudinal data
Statistical Theory and Related Fields, 2021 The main purpose of this paper is to investigate D-optimal population designs in multi-response linear mixed models for longitudinal data. Observations of each response variable within subjects are assumed to have a first-order autoregressive structure ...
Hongyan Jiang, Rongxian Yue
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson +20 more
wiley +1 more source
Optimality of nonlinear design techniques: A converse HJB approach [PDF]
, 1996 The issue of optimality in nonlinear controller design is confronted by using the converse HJB approach to classify dynamics under which certain design schemes are optimal.
Nevistić, Vesna, Primbs, James A.
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
Atovaquone smart lipid system: Design, statistical optimization, and in-vitro evaluation
Food Hydrocolloids for Health, 2023 The research was undertaken to design, develop and characterize the smart lipid system of an inadequate bioavailable Atovaquone (ATQ). The poor aqueous solubility and dissolution are the major constrain of inadequate bioavailability. The solubility study
Hardik Rana +3 more
doaj +1 more source
D-optimal designs formulti-response linear mixed models [PDF]
, 2018 Linear mixed models have become popular in many statistical applications duringrecent years. However design issues for multi-response linear mixed models are rarelydiscussed.
Liu, Xin, Wong, Weng Kee, Yue, Rong-Xian
core
Adaptive grid semidefinite programming for finding optimal designs [PDF]
, 2017 We find optimal designs for linear models using anovel algorithm that iteratively combines a semidefinite programming(SDP) approach with adaptive grid techniques.The proposed algorithm is also adapted to find locally optimaldesigns for nonlinear models ...
Dette, Holger +2 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Grasas y Aceites, 2017 The objective of the current study was to develop parameters for the separation of palmitic acid (PA) from a crude palm oil saturated fatty acid (SFAs) mixture by using the methanol crystallization method.
A. A.W. Japir +5 more
doaj +1 more source
Optimal group testing designs for estimating prevalence with uncertain testing errors [PDF]
, 2016 We construct optimal designs for group testing experiments where the goal is to estimate the prevalence of a trait by using a test with uncertain sensitivity and specificity.
Huang, Mong-Na Lo +3 more
core +3 more sources