Results 11 to 20 of about 4,627 (125)

Proteomic Profiling of Plasma to Uncover Novel Intervention Targets and Prognostic Biomarkers for Chronic Liver Diseases. [PDF]

Diabetes Obes Metab
ABSTRACT Aims The burden of chronic liver disease (CLD) is increasing. This study aims to identify protein markers for CLD and its progression, and develop a protein‐based risk prediction model. Materials and Methods We used proteome‐wide Mendelian randomization (MR), Bayesian colocalization and summary‐data‐based MR with proteomic data from deCODE ...
Li X, Sun J, Zhao J, Jiang F, Zhang M, Wu H, Yuan S, Li X, Lu J, Mantzoros CS.   +9 more
europepmc   +2 more sources

Spatial and developmental expression of key genes of terpene biosynthesis in Tanacetum parthenium

Biologia Plantarum, 2014
Feverfew (Tanacetum parthenium) is a medicinal plant belonging to the Asteraceae family. To improve understanding terpene metabolism in feverfew, the relative gene expression of four key genes coding 3-hydroxy-3-methylglutarylcoenzyme A reductase (HMGR ...
M. Majdi, G. Karimzadeh, M. A. Malboobi
doaj   +1 more source

Relative expression of genes of terpene metabolism in different tissues of Artemisia annua L

BMC Plant Biology, 2011
Background Recently, Artemisia annua L. (annual or sweet wormwood) has received increasing attention due to the fact that the plant produces the sesquiterpenoid endoperoxide artemisinin, which today is widely used for treatment of malaria.
Lundgren Anneli, Engström Alexander, Olofsson Linda, Brodelius Peter E   +3 more
doaj   +1 more source

RNA Sequencing Provides Insights into the Regulation of Solanesol Biosynthesis in Nicotiana tabacum Induced by Moderately High Temperature

Biomolecules, 2018
Solanesol is a terpene alcohol composed of nine isoprene units that mainly accumulates in solanaceous plants, especially tobacco (Nicotiana tabacum).
Ning Yan, Yongmei Du, Hongbo Zhang, Zhongfeng Zhang, Xinmin Liu, John Shi, Yanhua Liu   +6 more
doaj   +1 more source

Transcriptome and metabolome analysis to reveal major genes of saikosaponin biosynthesis in Bupleurum chinense

BMC Genomics, 2021
Background Bupleurum chinense DC. is a widely used traditional Chinese medicinal plant. Saikosaponins are the major bioactive constituents of B. chinense, but relatively little is known about saikosaponin biosynthesis.
Yilian He, Hua Chen, Jun Zhao, Yuxia Yang, Bin Yang, Liang Feng, Yiguan Zhang, Ping Wei, Dabin Hou, Junning Zhao, Ma Yu   +10 more
doaj   +1 more source

Differential Gene Expression and Withanolides Biosynthesis During in vitro and ex vitro Growth of Withania somnifera (L.) Dunal

Frontiers in Plant Science, 2022
Ashwagandha (Withania somnifera L. Dunal) is a medicinally important plant with withanolides as its major bioactive compounds, abundant in the roots and leaves.
Sachin Ashok Thorat, Arya Kaniyassery, Poornima Poojari, Melissa Rangel, Shashikala Tantry, Kodsara Ramachandra Kiran, Manjunath B. Joshi, Padmalatha S. Rai, Anna-Maria Botha, Annamalai Muthusamy   +9 more
doaj   +1 more source

Effects of abscisic acid on content and biosynthesis of terpenoids in Cannabis sativa at vegetative stage

Biologia Plantarum, 2012
The influence of abscisic acid (ABA) on plastidial and cytosolic terpenoids and on two key enzymes for terpenoid biosynthesis was determined in vegetative stage of Cannabis sativa L.
H. Mansouri, Z. Asrar
doaj   +1 more source

Overcoming Bottlenecks for Metabolic Engineering of Sesquiterpene Production in Tomato Fruits

Frontiers in Plant Science, 2021
Terpenoids are a large and diverse class of plant metabolites that also includes volatile mono- and sesquiterpenes which are involved in biotic interactions of plants.
Michael Gutensohn, Laura K. Henry, Scott A. Gentry, Joseph H. Lynch, Joseph H. Lynch, Thuong T. H. Nguyen, Eran Pichersky, Natalia Dudareva, Natalia Dudareva, Natalia Dudareva   +9 more
doaj   +1 more source

The Carotenogenesis Pathway via the Isoprenoid-β-carotene Interference Approach in a New Strain of Dunaliella salina Isolated from Baja California Mexico

Marine Drugs, 2009
D. salina is one of the recognized natural sources to produce β-carotene, and an useful model for studying the role of inhibitors and enhancers of carotenogenesis. However there is little information in D.
Luis Enrique Gutierrez-Millan, Jorge Olmos-Soto, Willian Capa-Robles, J. Paniagua-Michel   +3 more
doaj   +1 more source

Metabolite profiling and transcriptomic analyses demonstrate the effects of biocontrol agents on alkaloid accumulation in Fritillaria thunbergii

BMC Plant Biology, 2023
Background During Fritillaria thunbergii planting, pests and diseases usually invade the plant, resulting in reduced yield and quality. Previous studies have demonstrated that using biocontrol agents can effectively control grubs and affect the steroid ...
Xuemei Cheng, Dishuai Li, Zheng Jiang, Cheng Qu, Hui Yan, Qinan Wu   +5 more
doaj   +1 more source