Results 101 to 110 of about 15,581 (227)

A Biweekly GLP‐1R Agonist Designed With Drug‐Free Intervals for Enhanced Efficacy, Receptor Homeostasis and Gastrointestinal Tolerability

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11143-11177, December 2026.
ABSTRACT Aim To develop a next‐generation, longer‐acting, more‐clinical‐benefits agonist to achieve sustained efficacy with improved tolerability. Methods CT130 was designed from semaglutide. Binding affinity was validated via molecular dynamics and cellular assays.
Wei Ding   +4 more
wiley   +1 more source

Desbunde léxico. Internacionalismos en el arte chileno posgolpe

open access: yesArte e Investigación, 2017
El presente texto pretende retratar la presencia de manifestaciones artísticas acaecidas durante la dictadura militar chilena en el contexto editorial extranjero.
Vania Montgomery, Gastón J. Muñoz J.
doaj  

Irradiation‐Induced CD62L Shedding in Human Plasmacytoid Dendritic Cells Depends on ADAM17 and p38 MAPK

open access: yesImmunology, Volume 179, Issue 4, Page 671-681, December 2026.
Human plasmacytoid dendritic cell‐based vaccines efficiently migrate from blood to lymph nodes and prime naive T cells in humanised mice. Irradiation‐induced CD62L shedding, mediated by p38 MAP kinase and ADAM17, is involved in the regulation of PDC migration to secondary lymphoid organs in this model.
Estelle Leplus   +11 more
wiley   +1 more source

Induction of key immune pathways in mouse model of M.tuberculosis infection take places on D21 post infection.

open access: yes, 2013
B6 mice were infected with ∼100 CFU M.tuberculosis via the aerosol route and at specific times after infection, lung tissue was harvested and processed to extract RNA. cDNA microarray hybridization was used to study gene expression profiles on uninfected
Dongwan D. Kang (357725)   +4 more
core   +1 more source

Dynamic capabilities, preservation of socioemotional wealth, and family firm performance

open access: yesJournal of Innovation & Knowledge
This study examines the performance of family businesses through the theoretical lenses of dynamic capabilities and socioemotional wealth. A conceptual model is proposed, in which socioemotional wealth moderates the relationship between dynamic ...
Felipe Hernández-Perlines   +2 more
doaj   +1 more source

d_21 system: un juego para ser habitado

open access: yesInformes de la Construccion, 2008
d21_system es un prototipo de habitación transformable construido a base de S.3c (sistemas de construcción por componentes compatibles) que consiste en: 1- un catalogo de cabinas producidas en serie.
F. Altozano, J. M. Reyes
doaj   +1 more source

Основы регионоведения УД-№10744-уч

open access: yes, 2021
Учебная программа составлена на основе типового учебного плана D21-1-004/пр-тип. от 16.12.2020 и учебного плана БГУ D21-1-001/уч.
Репин, Виталий Валерьевич
core  

Unleashing the metaverse: Assessing the effects of China's city pilot policy on firm performance

open access: yesInternational Review of Economics & Finance
This study investigates the influence of the metaverse pilot city policy (MPCP) on firm performance using panel data from 127 China's A-share listed metaverse firms and a difference-in-differences (DID) model.
Lu Liu   +3 more
doaj   +1 more source

Viral Dynamic Model‐Informed Dose Selection of Mosnodenvir Prophylaxis against DENV‐3 in a Controlled Human Infection Model

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 5, Page 1379-1388, November 2026.
Dengue virus (DENV) infection is a significant global health threat. Mosnodenvir (JNJ‐64281802) is a pan‐serotype small molecule antiviral blocking DENV replication. A Phase IIa study (NCT05048875) evaluated the antiviral activity, safety, and pharmacokinetics of mosnodenvir as prophylaxis against DENV‐3 in a controlled human infection model (CHIM).
Nele Goeyvaerts   +8 more
wiley   +1 more source

Greenwashing: Motivations, causes and consequences

open access: yesInternational Review of Economics & Finance
We discuss motives and outcomes of corporate greenwashing as well as factors that contribute to it. We argue that in the presence of benefits accrued to corporate social responsibility, economic agents with short-term horizons may be incented to engage ...
Ali Fatemi, Iraj Fooladi, Greg Hebb
doaj   +1 more source

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