Results 71 to 80 of about 8,935 (210)
Integrated analysis with iCM‐SANS, SAXS and MD simulations for dynamics of multi‐domain proteins
Journal of Applied Crystallography, Volume 59, Issue 4, Page 1270-1281, August 2026.Segmental deuteration, combined with inverse contrast‐matching small‐angle neutron scattering (iCM‐SANS) and small‐angle X‐ray scattering (SAXS), provides structural constraints that improve discrimination of conformation ensembles of multi‐domain proteins derived from molecular dynamics (MD) simulations.Multi‐domain proteins (MDPs) adopt diverse ...
Aya Okuda +10 more
wiley +1 more source
Entry, Exit, and Market Structure in a Changing Climate
Social Science Research NetworkClimate change has long run effects on the size and composition of a country’s corporate sector. Using administrative data on the universe of Italian firms, we find that an increase in the incidence of very hot days over a multiyear period persistently ...
M. Cascarano +2 more
semanticscholar +1 more source
Clinical and Translational Science, Volume 19, Issue 8, August 2026.ABSTRACT Imlunestrant is a next‐generation, oral, selective estrogen receptor degrader approved for treating adults with estrogen receptor‐positive, human epidermal growth factor receptor 2‐negative, ESR1‐mutated advanced/metastatic breast cancer. Imlunestrant is metabolized partly by cytochrome P450 (CYP)3A4 oxidation and conjugation with glucuronic ...
Amita Datta‐Mannan +5 more
wiley +1 more source
PLoS ONE, 2019 Intravesical therapy using Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the most established cancer immunotherapy for bladder cancer. However, its underlying mechanisms are unknown. Mycolic acid (MA), the most abundant lipid of the BCG cell wall,
Takayuki Yoshino +13 more
doaj +1 more source
100 Years of Rising Corporate Concentration
The American Economic ReviewWe collect data on the size distribution of US businesses for 100 years, and use these data to estimate the concentration of production (e.g., asset share or sales share of top businesses). The data show that concentration has increased persistently over
S. Kwon, Yueran Ma, Kaspar Zimmermann
semanticscholar +1 more source
Learning by Necessity: Government Demand, Capacity Constraints, and Productivity Growth
The American Economic ReviewThis paper studies how firms adapt to demand shocks when facing capacity constraints. I show that increases in government purchases raise total factor productivity in quantity units at the production line level.
Ethan Ilzetzki
semanticscholar +1 more source
, 2014 The evaluation of the CHERMUG games was carried out in 3 phases which contributed in different ways to the game development and evaluation. Different cohorts of staff and students were involved in each phase and a detailed account of the list of pilot institutions is shown in Deliverable 21.
Boyle, Elizabeth +4 more
openaire +1 more source
Journal of Economics and ManagementAim/purpose – In line with the general trend of digitalization and changing customers’ needs and preferences, insurance companies have increasingly applied digital technology to their business.
Ćurak Marijana +2 more
doaj +1 more source
Journal of Ovarian ResearchOvarian aging is the main cause of reduced reproductive life span, yet its metabolic profiles remain poorly understood. This study aimed to reveal the metabolic homogeneity and heterogeneity between physiological and pathological ovarian aging.
Lihua Zeng +8 more
semanticscholar +1 more source
ESG ratings and firm performance: The moderating role of ESG rating disagreement
Borsa Istanbul ReviewWe examine the impact of ESG rating disagreement on the relationship between ESG ratings and firm performance. We find that ESG ratings are negatively associated with firm performance.
Chengcheng Liu, Qianhui Wu, Yu-En Lin
doaj +1 more source